Search for dissertations about: "Cellular transport"

Showing result 1 - 5 of 298 swedish dissertations containing the words Cellular transport.

  2. 1. The Hepatobiliary Transport of Rosuvastatin In Vivo

    Author : Ebba Bergman; Hans Lennernäs; Ulf Bondesson; Jack Cook; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rosuvastatin; Biliary excretion; Transport inhibition; Pharmacokinetics; Drug-drug interactions; Hepatobiliary transport; Organic anion transporting polypeptide; OATP; Statins; Gemfibrozil; Cyclosporine; Imatinib; Rifampicin; Canalicular transport; Sinusoidal transport; Hepatic uptake; Hepatic extraction; Biopharmacy; Biofarmaci; Biopharmaceutics; biofarmaci;

    Abstract : In vivo studies of hepatobiliary disposition are challenging. The hepatobiliary system is complex, as its physiological localization, complex cellular structure with numerous transporters and enzymes, and the interindividual variability in protein expression and biliary flow will all affect the in vivo disposition of a drug under investigation. READ MORE

  4. 2. Transport Analytics Based on Cellular Network Signalling Data

    Author : David Gundlegård; Johan M. Karlsson; Tommy Svensson; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Cellular networks of today generate a massive amount of signalling data. A large part of this signalling is generated to handle the mobility of subscribers and contains location information that can be used to fundamentally change our understanding of mobility patterns. READ MORE

  5. 3. Transport Modes in Nanotube-Vesicle Networks

    Author : Michal Tokarz; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; diffusion; confinement; liposome; biomimetic; micromanipulation; Vesicle; electrophoresis; network; nanotube; transport;

    Abstract : Methods for construction of surface-immobilized microscopic networks of phospholipid bilayer vesicles (3-50 µm in diameter) interconnected by lipid tubes (30-150 nm in radius), have previously been developed. The networks have controlled connectivity and are well-defined with regard to container size, content, angle between nanotube extensions, and nanotube length. READ MORE

  6. 4. Establishing the mechanistic basis of sugar transport

    Author : Abdul Aziz Qureshi; David Drew; Magnus Wolf-Watz; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane transport; transport energetics; nucleotide-sugar transporters; glucose transporters; malaria; cancer; Biochemistry; biokemi;

    Abstract : Sugar is a vital molecule required for cell viability and homeostasis. Sugar is important for metabolic energy, energy storage, signaling, structure and osmolyte regulation. Transport of sugar represents an important physiological process. READ MORE

  7. 5. Exploring Cellular Dynamics : From Vesicle Tethering to Cell Migration

    Author : Parham Ashrafzadeh; Johan Kreuger; Jonas Fuxe; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; cancer; cell migration; exocyst complex; exocytosis; FGD5; lipid rafts; plasma membrane; receptor trafficking; VEGFR2;

    Abstract : Cells in the body communicate with each other in order to cooperate efficiently. This communication is in part achieved by regulated secretion of signaling molecules, which when released from a cell may activate receptors present at the plasma membrane of an adjacent cell. Such signals affect both cell fate and behavior. READ MORE