Search for dissertations about: "Christian Smedman"

Found 1 swedish dissertation containing the words Christian Smedman.

2. 1. Toll-like receptor-induced cytokine secretion by human monocytes in healthy donors and septic patients assessed at the single cell level

   Author : Christian Smedman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Following the ligation of Toll-like receptors (TLRs) by bacterial-derived signature molecules, innate immune cells such as monocytes, macrophages and neutrophils initiate the inflammatory process by secreting chemokines and cytokines with a wide range of immunomodulatory effects. Under normal conditions, these mediators work to compartmentalize the inflammatory process and eradicate the intruder, while simultaneously recruiting more immune cells to the site of infection. READ MORE