Search for dissertations about: "Chromatin metabolism"

Showing result 1 - 5 of 27 swedish dissertations containing the words Chromatin metabolism.

2. 1. Long Noncoding RNA Mediated Regulation of Imprinted Genes

   Author : Faizaan Mohammad; Chandrasekhar Kanduri; Kristian Helin; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genomic imprinting; noncoding RNA; epigenetics; chromatin; DNA methylation; Developmental biology; Utvecklingsbiologi; Molecular biology; Molekylärbiologi; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Abstract : Genomic imprinting is an epigenetic phenomenon that causes a subset of mammalian genes to be expressed from only one allele in a parent-of-origin manner. The defects in the imprinting regulation result in disorders that affect development, growth and metabolism. READ MORE

4. 2. Myosin 1c taking adrenergic metabolism for a spin : More than a motor protein

   Author : Alice Åslund; Tore Bengtsson; Michael Czech; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glucose uptake; Glucose transporter; Brown adipose tissue; White adipose tissue; Skeletal muscle; Myosin1c; Nuclear myosin I; Physiology; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Metabolic diseases like type II diabetes (T2D) and obesity largely stems from an unbalanced energy homeostasis with the fails of the insulin pathway to the point in which the glucose homeostasis is severely disturbed leading to hyperglycemia. We have investigated if the β-adrenergic signaling pathways, in both brown adipose tissue (BAT) and skeletal muscle, could be used as a strategy to alleviate metabolic disease. READ MORE

5. 3. Studies on cholesterol and bile acid metabolism in Chinese cholesterol gallstone patients

   Author : Zhao-Yan Jiang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cholesterol gallstone disease; ABCG5 ABCG5; SRBI; ACAT2; Gender; Bile acids; Liver; Intestine;

   Abstract : Liver and intestine are important organs for the metabolism of cholesterol and bile acids in the body. Dysfunction in cholesterol and bile acid metabolism may lead to diseases such as cholesterol gallstone (GS) disease and atherosclerosis. READ MORE

6. 4. Genetic analysis of cell cycle and chromatin regulation in quiescent fission yeast cells

   Author : Yasaman Zahedi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : During proliferation, cells produce their genetic materials to increase the number of cells, while in the absence of nutrients or by the induction of stimulus, the proliferative phase is stopped and entry into quiescence is triggered to increase their chance of survival. Quiescence is a reversible resting phase where cells enter, in case of nutrient deprivation or damage and induced by stimuli. READ MORE

7. 5. Evolution of Yeast Respiro-Fermentative Lifestyle and the Underlying Mechanisms Behind Aerobic Fermentation

   Author : Arne Hagman; Biologiska institutionen; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Crabtree effect; aerobic fermentation; respiro-fermentation; ethanol production; yeast; central carbon metabolism; evolution of alternative lifestyles;

   Abstract : Under aerobic conditions, most yeasts such as Kluyveromyces lactis, prefer the respiratory pathway and some, such as Saccharomyces cerevisiae prefer less energy efficient fermentative pathway for their energy metabolism. These two metabolic strategies are also known as Crabtree negative and Crabtree positive respectively, and the evolution of the latter has lately been explained by the “make-accumulate-consume” life strategy. READ MORE