Search for dissertations about: "Citrulline"
Showing result 1 - 5 of 29 swedish dissertations containing the word Citrulline.
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1. Regulation of cytokine-induced nitric oxide production in insulin-producing cells
Abstract : Cytokine-induced expression of the inducible form of nitric oxide synthase (iNOS) and production of nitric oxide (NO) may contribute to pancreatic β-cell damage during the development of type 1 diabetes. iNOS catalyses the conversion of arginine into citrulline and NO, a reaction regulated by the amount of expressed iNOS enzyme and by the cellular availability of arginine. READ MORE
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2. Anti-citrulline immunity in rheumatoid arthritis : characterization of peptide-HLA interactions and CD4+ T cell responses
Abstract : Rheumatoid Arthritis (RA) is a complex, systemic autoimmune disorder characterized by chronic inflammation in small joints in hands and feet. It is a common disease that if untreated leads to joint destruction, disability, comorbidities and a reduced lifespan. READ MORE
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3. Diversity and function of anti-modified protein autoantibodies in rheumatoid arthritis
Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune disease particularly affecting synovial joints. Anti-citrullinated protein autoantibodies (ACPA) are detected in the serum of about 2/3 of RA patients and are being used to classify the disease. READ MORE
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4. Nitric oxide, arginine and acute pancreatitis
Abstract : Acute pancreatitis is a serious inflammatory condition which is managed symptomatically as there is no causal treatment to offer. The main background causes are alcohol abuse and gallstone disease. The inducing factors lead to a premature activation of pancreatic enzymes in the acinar cells and their subsequent release into the pancreatic tissue. READ MORE
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5. The influence of nitric oxide and cholecystokinin on tissue homeostasis in exocrine pancreas : an experimental study in rats
Abstract : Growth of the pancreas is stimulated by cholecystokinin (CCK) in rats. Nitric oxide (NO), which is synthesized from the amino acid L-arginine by NO-synthases (NOS), interferes with CCK in modulating the pancreatic secretion. READ MORE