Search for dissertations about: "Clinical chemistry"

Showing result 1 - 5 of 250 swedish dissertations containing the words Clinical chemistry.

2. 1. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence

   Author : Erik Chorell; Fredrik Almqvist; Stephen Hanessian; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pilicide; curlicide; anti-virulence; chaperone usher pathway; antibacterial; pili; curli; Escherichia coli; biofilm inhibitor; 2-pyridone; peptidomimetic; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi; Pharmaceutical chemistry; Läkemedelskemi; Organic synthesis; Organisk syntes; Infectious diseases; Infektionssjukdomar; Biorganic Chemistry; bioorganisk kemi; Infectious Diseases; infektionssjukdomar; datorlingvistik; computational linguistics; organisk kemi; Organic Chemistry;

   Abstract : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. READ MORE

4. 2. Insights into Covalent Chemistry for the Developmen­t of Biomaterials

   Author : Daniel Bermejo-Velasco; Oommen P. Varghese; Jöns Hilborn; Frey Holger; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hyaluronic acid; hydrogel; biomaterials; covalent chemistry; biomedical applications; MRI; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry;

   Abstract : Covalent cross-linking chemistry is currently exploited in the preparation of biomaterial for biomedical applications. Choice of these chemistries for the preparation of biomaterials and bioconjugates strongly influences the biological output of these materials. READ MORE

5. 3. Extracellular Matrix Based Materials for Tissue Engineering

   Author : Cecilia Aulin; Jöns Hilborn; Tim Bowden; Laura Creemers; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Extracellular matrix; collagen synthesis; bioreactor; cell culture; bone morphogenetic protein-2; noggin; hyaluronan; cartilage; Medical technology; Medicinsk teknik; Molecular biology; Molekylärbiologi; Orthopaedics; Ortopedi; Transplantation surgery; Transplantationskirurgi; Biomaterials; Biomaterial; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Cell and molecular biology; Cell- och molekylärbiologi; Polymer chemistry; Polymerkemi; Materials chemistry; Materialkemi; cellforskning; Cell Research; materialvetenskap; Materials Science; medicinsk cellbiologi; Medical Cell Biology; ortopedi; Orthopaedics;

   Abstract : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. READ MORE

6. 4. The Use of Laboratory Analyses in Sweden : Quality and Cost-Effectiveness in Test Utilization

   Author : Mirja Mindemark; Anders Larsson; Lars-Olof Hansson; Per Simonsson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; continuing medical education; cost control; cost savings; physician practice patterns; diagnostic tests; clinical chemistry; primary health care; health care costs; laboratory management; test utilization; trends; cost-effectiveness; inflammatory bowel disease; irritable bowel syndrome; calprotectin; cost avoidance; Clinical chemistry; Klinisk kemi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap;

   Abstract : Laboratory analyses, essential in screening, diagnosis, treatment, and monitoring of disease, are indispensable in health care, but appropriate utilization is intricate. The overall aim of this thesis was to study the use of laboratory tests in Sweden with the objective to evaluate and optimize test utilization. READ MORE

7. 5. Mutant superoxide dismutase-1-caused pathogenesis in amyotrophic lateral sclerosis

   Author : Daniel Bergemalm; Stefan Marklund; Thomas Brännström; Peter Andersen; Caterina Bendotti; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD1; mitochondria; proteome; transgenic mice; inclusion; Clinical chemistry; Klinisk kemi; biokemi; Biochemistry; neurologi; Neurology; Clinical Chemistry; klinisk kemi; patologi; Pathology;

   Abstract : Amyotrophic lateral sclerosis (ALS) is a devastating disease that affects people in their late mid-life, with fatal outcome usually within a few years. The progressive degeneration of neurons responsible for muscle movement (motor neurons) throughout the central nervous system (CNS) leads to muscle wasting and paralysis, and eventually affects respiratory function. READ MORE