Search for dissertations about: "Cyclization"
Showing result 1 - 5 of 41 swedish dissertations containing the word Cyclization.
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1. Palladium(II)-Catalyzed Oxidative Cyclization Strategies : Selective Formation of New C-C and C-N Bonds
Abstract : The main focus of this thesis has been directed towards preparation and oxidative carbocyclization of en-, dien- and aza-enallenes.In the first part of this thesis, a stereoselective oxidative carbocyclization of dienallenes was realized. READ MORE
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2. Construction of Five-Membered Heterocyclic Compounds via Radical Cyclization
Abstract : This thesis describes how radical cyclization chemistry can be applied for the construction of heterocyclic compounds.In the first part, a series of electron deficient α-phenylselenenylalkenes were prepared via a PhSeCl-addition/HCl-elimination sequence. READ MORE
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3. Radical Cyclization Approaches to Pyrrolidines
Abstract : Five-membered rings are readily prepared by 5-exo-trig radical cyclization. This thesis is concerned with novel methodology for pyrrolidine synthesis. We have synthesised selenium containing radical precursors from aziridines and α-phenylseleno ketones, and cyclized them to 2,4- and 3,4-disubstituted pyrrolidines. READ MORE
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4. Synthesis of Aldehyde-Functionalized Building Blocks and Their Use for the Cyclization of Peptides : Applications to Angiotensin II
Abstract : This study addresses the issue of how to convert peptides into drug-like non- peptides with retained biological activities at peptide receptors. Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, Ang II) was used as a model peptide. READ MORE
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5. Pyrrolidines via Radical Cyclization
Abstract : .... READ MORE