Search for dissertations about: "DELIVERY"
Showing result 1 - 5 of 1792 swedish dissertations containing the word DELIVERY.
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1. Drug Delivery to the Brain by Liposomes : Understanding Factors Governing Delivery Outcomes In Vivo
Abstract : The blood-brain barrier (BBB) is the primary obstacle for efficient drug delivery to the central nervous system (CNS). One promising strategy to enhance brain delivery is to utilize nanocarriers (NC), e.g., liposomes, encapsulating CNS drugs. READ MORE
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2. Rational modifications of cell-penetrating peptides for drug delivery : Applications in tumor targeting and oligonucleotide delivery
Abstract : High molecular weight biomolecules are becoming important in the development of new therapeutics. However, their size and nature creates a major limitation for their application – poor penetration through biological membranes. READ MORE
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3. Translational Tumor Drug Delivery : Doxorubicin formulation performance, intracellular uptake and molecular diffusion
Abstract : Globally, hepatocellular carcinoma (HCC) is the most common form of liver cancer and a leading cause of cancer death. One important risk factor is liver cirrhosis and the disease progression is characterized by deposition of extracellular matrix proteins that form a fibrous network, which increases liver stiffness and may limit the effectiveness of different treatment strategies. READ MORE
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4. Nasal Drug Delivery : In Vitro Studies on Factors Influencing Permeability and Implications on Absorption
Abstract : Nasal delivery is a feasible alternative to oral or parenteral administration for some drugs because of the high permeability of the nasal epithelium, rapid drug absorption across this membrane and avoidance of hepatic first-pass metabolism. The main objective of this thesis was to investigate factors influencing the permeability of the nasal mucosa to various compounds and to evaluate implications for drug absorption via the nasal route. READ MORE
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5. Ocular drug delivery : studies on corneal permeability and an evaluation of prostaglandin F2a pro-drugs and sodium hyaluronate
Abstract : .... READ MORE