Search for dissertations about: "DEXTRAN SULFATE"

Showing result 1 - 5 of 13 swedish dissertations containing the words DEXTRAN SULFATE.

  2. 1. Dynamic changes in T cell compartments and new approaches in evaluating DSS induced and Gai2 deficient colitis

    Author : Maria Fritsch Fredin; Göteborgs universitet; []
    Keywords : colitis; Gai2- - mice; dextran sodium sulfate; ex vivo cultures; micro-Computed Tomography; IEL; thymus; Inflammatory Bowel Disease;

    Abstract : The overall aim of this thesis was to increase the understanding of the immunopathology of Inflammatory Bowel Disease (IBD). The first aim was to elucidate how the thymus and the gut epithelium were affected by colitis. The second aim was to investigate new ways of assessing and monitoring colitis. READ MORE

  4. 2. Intracellular regulation of TLR signaling Basic mechanisms and importance in intestinal inflammation

    Author : Martin Berglund; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TLR IL-1R signalling; Gαi2- - mice; IRAK; peritoneal macrophages; cross-tolerance; dextran sulfate sodium; IBD;

    Abstract : Toll-like receptors (TLRs) recognize conserved structures on/in microorganisms. The intracellular signalling pathways of TLRs are shared with IL-1R and IL-18R and their activation leads to transcription of proinflammatory cytokines and type-I interferons. READ MORE

  5. 3. Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients

    Author : Kristina Elgbratt; Göteborgs universitet; []
    Keywords : Inflammatory bowel diseaseInflammatory bowel disease; G?i2- - mice; dextran sodium sulfate; thymocytes; T cell receptor excision circles TRECs ; resent thymic emigrants;

    Abstract : Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in G?i2-deficient and DSS-induced Colitis as well as in IBD patients Kristina Elgbratt Department of Microbiology and Immunology, Institute of Biomedicine, The Sahlgrenska Academy, G?teborg University, G?teborg Sweden Inflammatory Bowel Disease (IBD) is a chronic relapsing inflammatory disorder of the gastrointestinal tract, comprising ulcerative colitis and Crohn?s disease. READ MORE

  6. 4. Mechanisms and Therapeutic Interventions of Instant Blood-Mediated Inflammatory Reaction (IBMIR)

    Author : Helena Johansson; Bo Nilsson; Olle Korsgren; Kristina Nilsson-Ekdahl; Tomas Lindahl; Uppsala universitet; []
    Keywords : Immunology; Diabetes; Islet transplantation; Islets of Langerhans; Coagulation activation; Complement activation; IBMIR; Tissue factor; Low molecular weight dextran sulfate; Immunologi;

    Abstract : Intraportal transplantation of isolated islets of Langerhans is a procedure approaching clinical acceptance as a treatment for patients with type I diabetes mellitus. One major problem with this treatment is that large amounts of cells are lost at the time of infusion into the portal vein, resulting in a low level of engraftment of the islets. READ MORE

  7. 5. Studies of Carbohydrate-Binding Proteins from Enterotoxigenic Escherichia coli

    Author : Lena Jansson; Göteborgs universitet; []
    Keywords : Carbohydrate recognition; ETEC colonization factors; CFA I fimbriae; CS6 protein; heat-labile enterotoxin;

    Abstract : Knowledge about the carbohydrate binding specificity of pathogens can give an increased understanding of their virulence strategies, and is also of importance for the development of anti-adhesive therapies and vaccines. Enterotoxigenic Escherichia coli (ETEC) is a well-known causative agent of diarrheal disease. READ MORE