Search for dissertations about: "DLBCL"

Showing result 21 - 25 of 44 swedish dissertations containing the word DLBCL.

  2. 21. Estrogens and lymphoma growth

    Author : Muhammad Sharif Hasni; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Lymphomas are generally not considered as endocrine-associated cancers. Nevertheless, most lymphoid malignancies show a gender differencein incidence and prognosis, with males being more affected.The molecular mechanism for this gender difference is unknown. READ MORE

  4. 22. Biomarker Discovery in Cancer using Affinity Proteomics - Studies of B-cell lymphomas and Breast Cancer

    Author : Frida Pauly; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; affinity proteomics; antibody microarray; cancer; B-cell lymphoma; breast cancer; biomarker discovery;

    Abstract : The continual increase in incidence of cancer has created an urgent need for improved methods for diagnosis, prognosis and/or treatment. In this context, the field of biomarker research has expanded immensely during the last few years. This thesis, based on four original papers, revolves around protein biomarker discovery in cancer. READ MORE

  5. 23. Burkitt lymphoma and diffuse large B-cell lymphoma – therapeutic strategies and pathogenetic mechanisms

    Author : Tove Wästerlid; Tumörmikromiljö; []
    Keywords : Burkitt Lymphoma; Chemotherapy; SOX11; Diffuse large B-cell lymphoma; Prognostic factors; Rituximab;

    Abstract : Burkitt lymphoma (BL) is a rare, aggressive disorder constituting 1% of all non-Hodgkin lymphoma. Diffuse large B-cell lymphoma (DLBCL) is more common, accounting for 30% of malignant lymphoma. Standard treatment for adult BL and for certain subgroups of patients with DLBCL remains to be defined due to paucity of randomised trials performed. READ MORE

  6. 24. Estrogen regulation of non-Hodgkin lymphomas and its underlying mechanisms

    Author : Dan Huang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Most non-Hodgkin lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL) and mantle cell lymphoma (MCL), show a higher male to female incidence ratio. The reason for this is not clear, but epidemiological and experimental studies have suggested a role for estrogens in NHL acting via estrogen receptor β (ERβ). READ MORE

  7. 25. Clinical and functional aspects of microRNA regulation in human cancers

    Author : Stefano Caramuta; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : miRNAs are short single-stranded non-coding RNAs which regulate gene expression at the post-transcriptional level in many biological processes, including proliferation, apoptosis and differentiation. A number of studies have shown the importance of miRNAs in carcinogenesis and accumulating evidence supports their role as diagnostic and prognostic biomarkers in human cancers. READ MORE