Search for dissertations about: "DLI"

Showing result 1 - 5 of 11 swedish dissertations containing the word DLI.

2. 1. Leukaemic relapse after allogeneic haematopoietic stem cell transplantation and the use of the graft-versus-leukaemia effect

   Author : Stefan Carlens; Karolinska Institutet; Karolinska Institutet; []
   Keywords : haematopoietic stem cell transplantation; GVHD; GVL; DLI; T-cell culture; retroviral transduction; NK-cell culture;

   Abstract : Survival after allogeneic haematopoietic stem cell transplantation (HSCT) has improved over the last decades due to improvements in immunosuppressive regimens and supportive care. Today the major risk of treatment failure is recurrent leukaemia, a risk which has stayed relatively constant over the years. READ MORE

4. 2. Umbilical cord blood transplantation : clinical outcome, chimerism development, and in vitro expansion of T-cells for clinical use

   Author : Sofia Berglund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Umbilical cord blood (UCB) is an alternative graft source in allogeneic hematopoietic stem cell transplantation (HSCT). The unique advantages with UCB as a stem cell source are found in the permissibility for human leukocyte antigen (HLA)-mismatch, rapid availability, and comparatively risk-free graft collection. READ MORE

5. 3. A 'new public health' perspective on building competence for end-of-life care and communication : how death literacy can be developed and measured

   Author : Therese Johansson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Due to aging populations and prolonged dying trajectories in many high-income countries including Sweden, more people will need extended periods of care and support at the end-of-life (EOL). In light of these changes, EOL care provision is increasingly recognized as a public health issue to be addressed not only within but also beyond the health care system. READ MORE

6. 4. Primary immunodeficiency in southern Sweden. Strategies for diagnosis and clinical management

   Author : Nicholas Brodszki; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune system; Lymphocytes; T-cell; B-cell; Antibodies; Complement system; Epidemiological study; Primary immunodeficiency; Severe combined immunodeficiency; Hematopoietic stem cell transplantation;

   Abstract : The overall aim of this PhD project was to gain insight into the incidence of primary immunodeficiency (PID) in southern Sweden and to optimize diagnostic and treatment measures for these patients. We estimated the occurrence rate of PID in the pediatric population of southern Sweden during a period of 4 years and described the demographic, clinical and immunological characteristics of the identified cases. READ MORE

7. 5. Methods and biomarkers for outcome prediction after allogeneic hematopoietic stem cell transplantation

   Author : Darius Sairafi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Allogeneic hematopoietic stem cell transplantation (HSCT) is a potent immunotherapeutic procedure but its usability is limited by a high risk of serious complications. A prerequisite for timely initiation of preventive measures is the availability of predictive methods. READ MORE