Search for dissertations about: "DNA compaction"

Showing result 1 - 5 of 25 swedish dissertations containing the words DNA compaction.

  2. 1. DNA Compaction at Surfaces

    Author : Marité Cárdenas; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Polymer technology; Fysikalisk kemi; Physical chemistry; gränsskikt; Ytkemi; Surface and boundary layery chemistry; cationic amphiphiles; DNA; Polymerteknik; surface; biopolymers;

    Abstract : The interfacial behavior of DNA and DNA-cationic surfactant has been studied. Particular attention was paid to the type of cationic surfactant and the DNA conformation (single or double stranded) as well as the DNA length. READ MORE

  4. 2. Controlling DNA compaction and the interaction with model biomembranes

    Author : Marie-Louise Ainalem; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; model biomembrane; DNA compaction; cryo-TEM; null ellipsometry; dynamic light scattering; toroid; bilayer; neutron reflectivity; dendrimer; PAMAM; DNA; poly amido amine ;

    Abstract : The studies described in this thesis forms part of a larger collaborative project, Neonuclei, with the objective to design a module for packaging the negatively charged DNA into a ”neonucleus” with transcription competence. There are many applications that require control of DNA compaction, i.e. packaging or condensation. READ MORE

  5. 3. Association of Amphiphiles and Polyelectrolytes with DNA

    Author : Yulia S Mel'nikova; Fysikalisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; cryo-TEM; SAXS; fluorescence microscopy; DNA condensation; DNA-polyelectrolyte; DNA- amphiphile interactions; Fysikalisk kemi;

    Abstract : DNA- cationic amphiphile and DNA-cationic polymer systems were studied with respect to the intermolecular interactions, as well as structure and stability of formed complexes. The thesis is divided in two parts: one section is a summary and the other section contains five papers. READ MORE

  6. 4. Protein Folding and DNA Origami

    Author : Mark Marvin Seibert; David van der Spoel; Helmut Grubmüller; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein folding; Molecular Dynamics simulations; DNA origami; Biophysics; Biofysik; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : In this thesis, the folding process of the de novo designed polypeptide chignolin was elucidated through atomic-scale Molecular Dynamics (MD) computer simulations. In a series of long timescale and replica exchange MD simulations, chignolin’s folding and unfolding was observed numerous times and the native state was identified from the computed Gibbs free-energy landscape. READ MORE

  7. 5. DNA Tetraplexes and Nucleosome Positioning Sequences

    Author : Tomas Simonsson; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Nucleosome; myc; gene expression; oncogene; DNA tetraplex;

    Abstract : All eukaryotic organisms package their genomes into a nucleoprotein complex known as chromatin, whose major constituents are the DNA and proteins known as histones. The non-covalent association of histones with DNA results in considerable compaction and allows the organisation of the genome into the cell nucleus. READ MORE