Search for dissertations about: "DNA sensing"

Showing result 1 - 5 of 44 swedish dissertations containing the words DNA sensing.

  1. 1. Digital Electrical DNA Sensing

    Author : Maoxiang Guo; Wouter van der Wijngaart; Fredrik Westerlund; KTH; []
    Keywords : DNA detection; thiol-ene-epoxy; rolling circle amplification; digital measurement; DNA stretching; microwell-array; gold nanowires; electrical measurement; specificity; limit of detection; liquid storage; disease diagnosis; lab-on-a-chip; point-of-care.;

    Abstract : Molecule detection is a workhorse in life sciences and medicine, for example in cancer diagnosis and virus and bacterial detection. DNA analysis can provide vital information about the state of a host organism and its medical and health condition. READ MORE

  2. 2. Silicon Nanopore Arrays : Fabrication and Applications for DNA Sensing

    Author : Miao Zhang; Jan Linnros; Meni Wanunu; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanopore; array; electrochemical etching; DNA; optics; thermophoresis;

    Abstract : Nanopore biomolecule sensing and sequencing has emerged as a simple but powerful tool for single molecule studies over the past two decades. By elec- trophoretically driving single molecules through a nanometer-sized pore, often sitting in an insulating membrane that separates two buffer solutions, ionic current blockades can be detected to reveal rich information of the molecules, such as DNA length, protein size and conformation, even nucleic acid se- quence. READ MORE

  3. 3. Biological Sensing and DNA Templated Electronics Using Conjugated Polymers

    Author : Per Björk; Olle Inganäs; Wolfgang Fritzsche; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; conjugated polymer; conjugated polyelectrolyte; DNA; sensor; nanowire; Bioengineering; Bioteknik;

    Abstract : Conjugated polymers have been found useful in a wide range of applications such as solar cells, sensor elements and printed electronics, due to their optical and electronic properties. Functionalization with charged side chains has enabled water solubility, resulting in an enhanced interaction with biomolecules. READ MORE

  4. 4. Engineering Surfaces of Solid-State Nanopores for Biomolecule Sensing

    Author : Shiyu Li; Shi-Li Zhang; Michael Mayer; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; solid-state nanopores; surface engineering; DNA sensing; DNA polymerase; optical detection; lipid bilayer; hafnium oxide; electron beam induced deposition;

    Abstract : Nanopores have emerged as a special class of single-molecule analytical tool that offers immense potential for sensing and characterizing biomolecules such as nucleic acids and proteins. As an alternative to biological nanopores, solid-state nanopores present remarkable versatility due to their wide-range tunability in pore geometry and dimension as well as their excellent mechanical robustness and stability. READ MORE

  5. 5. Electric DNA chips for determination of pathogenic microorganisms

    Author : Yanling Liu; Sven-Olof Enfors; Thomas Schweder; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; electric DNA chip array; fast determination; virulence genes; multiplexed gene detection; bacterial colony; ultrasonication; DNA fragmentation; Bacillus cereus; Biology; Biologi; Bioengineering; Bioteknik;

    Abstract : Silicon-based electric DNA chip arrays were utilized to fast identify pathogenic microorganisms with respect to the capacity to produce toxins involved in foodborne poisoning and infections. Bacteria of the B. cereus and the enterohemorrhagic E. READ MORE