Search for dissertations about: "DNA technology"

Showing result 1 - 5 of 553 swedish dissertations containing the words DNA technology.

  2. 1. Selector Technology : For Multiplex DNA Analysis

    Author : Fredrik Dahl; Mats Nilsson; Ulf Landegren; Ivo Glynne Gut; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; DNA technology; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : A majority of methods for identifying sequences in the human genome involve target sequence amplification through PCR. This work presents novel methods for amplifying circularized DNA and presents solutions for some major limitations of PCR. READ MORE

  4. 2. Single DNA Molecule Analysis – New Tools for Medical Diagnosis

    Author : My Nyblom; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; optical DNA mapping; DNA damage; DNA; single-molecule analysis; fluorescence microscopy; antibiotic resistance; nanofluidics; genetics;

    Abstract : The DNA molecule, the blueprint of life, contains an enormous amount of information. The information is coded by the combination of four bases; adenine, cytosine, guanine, and thymine, that, together with the sugar-phosphate backbones, make up the DNA double helix. READ MORE

  5. 3. Microfluidic Preparation and Transport of Long DNA using Pillar Arrays

    Author : Oskar Ström; NanoLund: Centre for Nanoscience; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microfluidics; Deterministic Lateral Displacement; DNA Separation; Elastic Turbulence; Micro-pillar arrays; DNA Sample Preparation; Lab-on-a chip; elastic waves; Sample Preparation; DNA Isolation; bumper array; Fysicumarkivet A:2023:Ström;

    Abstract : This thesis presents a set of microfluidic tools and experimental studies for preparing (> 20 kbp) for genetic analysisas well as the transport of high-concentration, long-DNA solutions in pillar arrays.Long-DNA sample preparation with conventional gel-based techniques is slow (tens of hours to days) and laborious. READ MORE

  6. 4. Mitochondrial DNA : analysis of the control region in forensic and population genetic studies

    Author : Peter Savolainen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; mitochondrial DNA; control region; tandem repeats; D-loop; homoplasmy; hair; forensic; microsatellites; evolution; DNA sequencing; PCR; domestic dog; wolf; Bioengineering; Bioteknik;

    Abstract : .... READ MORE

  7. 5. Silicon Nanopore Arrays : Fabrication and Applications for DNA Sensing

    Author : Miao Zhang; Jan Linnros; Meni Wanunu; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; nanopore; array; electrochemical etching; DNA; optics; thermophoresis;

    Abstract : Nanopore biomolecule sensing and sequencing has emerged as a simple but powerful tool for single molecule studies over the past two decades. By elec- trophoretically driving single molecules through a nanometer-sized pore, often sitting in an insulating membrane that separates two buffer solutions, ionic current blockades can be detected to reveal rich information of the molecules, such as DNA length, protein size and conformation, even nucleic acid se- quence. READ MORE