Search for dissertations about: "DNA-binding"
Showing result 1 - 5 of 274 swedish dissertations containing the word DNA-binding.
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1. Mouse polyomavirus large T-antigen : DNA-binding and related activities
Abstract : .... READ MORE
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2. The adenovirus DNA-binding protein : structure and function
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3. Characterization of the DNA-Binding Properties of the Cyanobacterial Transcription Factor NtcA
Abstract : Nitrogen is an essential building block of proteins and nucleic acids and, therefore, crucial for the biosphere. Nearly 79 % of the air consists of nitrogen, but in the form of nitrogen gas (N2), which cannot be utilized by most organisms. READ MORE
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4. Structural Studies of Flexible Biomolecules and a DNA-binding Protein
Abstract : The knowledge of the three-dimensional structures of proteins and polypeptides is essential to understand their functions. The work shown in this thesis has two objectives. READ MORE
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5. Exploring new strategies of controlling DNA binding
Abstract : Abstract Due to the increasing knowledge about DNA structure and function, as well as the fact that the sequence of the human genome is now known, DNA becomes more and more interesting as a drug target, especially for treatment of genetic diseases and cancer, but also for treatment of diseases caused by pathogens. However, one of the major challenges is to achieve specificity - in the case of genetic diseases to uniquely target a specific gene and in the case of the cancer and pathogens to target specific cells. READ MORE