Search for dissertations about: "DSPC liposomes"

Found 2 swedish dissertations containing the words DSPC liposomes.

  2. 1. Two-Step Targeting for Effective Radionuclide Therapy : Preclinical Evaluation of 125I-labelled Anthracycline Delivered by Tumour Targeting Liposomes

    Author : Amelie Fondell; Lars Gedda; Detlef Gabel; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radionuclide; Auger electrons; liposomes; targeting; tumour therapy; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Abstract : For the treatment of cancer, Auger-electron emitting radionuclides are strongly dependent on their close proximity to DNA to utilize the local therapeutic potential of the Auger electrons. This thesis investigates a two-step targeting approach that uses targeting liposomes for the delivery of an Auger-electron emitter, 125I, coupled to a DNA-binding compound, Comp1, to the tumour-cell DNA. READ MORE

  4. 2. Studying the influence of the physicochemical properties of lipid nanoparticles for mucosal vaccine delivery

    Author : Karin Norling; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; influenza; nanoparticles; CTA1-DD; liposomes; dendritic cells; lipodisks; antigen presentation; flow cytometry; vaccine carriers; TIRF microscopy;

    Abstract : Lipid-based nanoparticles have attracted attention as promising pharmaceutical carriers. Reports of them having inherent adjuvant properties make them particularly interesting as vaccine vectors; however, the physicochemical profile of an ideal nanoparticle for mucosal vaccine delivery remains unknown. READ MORE