Search for dissertations about: "Desflurane"

Showing result 1 - 5 of 6 swedish dissertations containing the word Desflurane.

  2. 1. Ventilation/Perfusion Matching and its Effect on Volatile Pharmacokinetics

    Author : Moritz Andreas Kretzschmar; Anders Larsson; Jan Jakobsson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anesthesia; Animal models in research; Mass spectrometry; Gas chromatography; MIGET; Ventilation-perfusion; Desflurane; Isoflurane; Bronchoconstriction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Abstract : The mismatching of alveolar ventilation and perfusion (VA/Q) is the major determinant of impaired gas exchange. The gold standard for analyzing VA/Q distribution is the multiple inert gas elimination technique (MIGET), conventionally based on gas chromatography (GC), and, although simple in principle, a technically demanding procedure limiting its use. READ MORE

  4. 2. The Immune Response to One-Lung Ventilation : Clinical and Experimental Studies

    Author : Thomas Schilling; Göran Hedenstierna; Hans Hedenström; Thomas Hachenberg; Sven-Erik Ricksten; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; Medical laboratory science; Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

    Abstract : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. READ MORE

  5. 3. Modern inhalation agents and effects of anaesthesia equipment during low-flow anaesthesia

    Author : Anders Johansson; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anestesiologi; intensive care; intensivvård; Anaesthesiology; humidity and temperature; heat and moisture exchanger; isoflurane; desflurane; sevoflurane; anaesthetics volatile; carbon dioxide absorber; Low-flow; re-breathing circle circuit;

    Abstract : Volatile agents are economically and ecologically acceptable only when administered via low-flow systems. However, sevoflurane degrades during low-flow anaesthesia to compound A, and a high carbon dioxide absorber temperature increases this degradation. READ MORE

  6. 4. Genetic and cognitive aspects on recovery after propofol anaesthesia

    Author : Marja Lindqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : propofol;

    Abstract : Propofol is one of the most used intravenous anaesthetics in the western world. It is often used for ambulatory surgery due to favourable pharmacokinetic properties allowing quick onset and short emergence time. However, there is considerable interindividual variation in pharmacokinetics and dynamics as well as gender differences. READ MORE

  7. 5. Anaesthesia and analgesia for surgery in rabbits and rats : a comparison of the effects of different compounds

    Author : Patricia Hedenqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Studies of anaesthesia and analgesia in rats and rabbit were undertaken with the aim to improve anaesthesia techniques, for better animal welfare and research quality. Induction of anaesthesia with the volatile halogenated agents isoflurane, sevoflurane and desflurane was compared in the New Zealand White rabbit. READ MORE