Search for dissertations about: "Diffuse large B-cell lymphoma karolinska"

Showing result 1 - 5 of 30 swedish dissertations containing the words Diffuse large B-cell lymphoma karolinska.

  2. 1. Genetics of diffuse large B-cell lymphoma

    Author : Konstantinos Georgiou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diffuse large B-cell lymphoma (DLBCL) is one the most common forms of non-Hodgkin lymphoma and one of the most aggressive B-cell neoplasms. Although most patients respond to current standard treatments, a significant number of them relapse and become refractory to treatment. Hence, there is a need for new approaches in the management of DLBCL. READ MORE

  4. 2. Regulation of molecular processes in diffuse large B-cell lymphoma

    Author : Therese Högfeldt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The molecular understanding of diseases has advanced rapidly due to the use of gene expression profiling. However, these methods have been hampered by the limitation to use frozen tissue specimens. Formalin fixation and paraffin embedding (FFPE) is a standard procedure for long time storage of tissues. READ MORE

  5. 3. TRIM21/ Ro52 in B cell pathology

    Author : Susanna Brauner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease affecting 0.2% of the population. Several B cell aberrances have been linked to pSS, such as autoantibody production, hypergammaglobulinemia and B cell associated genetic polymorphisms. In addition, pSS patients display a 16 fold increased risk to develop B cell lymphomas. READ MORE

  6. 4. Real-world studies on B-cell malignancies

    Author : Anna Asklid; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Randomized controlled trials remain the preferred way of evaluating new treatments. However, in studies on malignancies, trial data may not always be sufficient to address the requirements of health care providers and regulatory agencies regarding recommendations as patients are strictly selected through inclusion- and exclusion criteria. READ MORE

  7. 5. Diffuse large B-cell lymphoma : population-based studies of relapse and cardiac complications

    Author : Sara Harrysson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Diffuse large B-cell lymphoma (DLBCL) is an aggressive life-threatening disease, but it is often possible to cure with immunochemotherapy. Not responding to primary treatment or having a relapse is associated with poor prognosis. However, it has not been well described how large the proportion of patients with relapsed/refractory disease is. READ MORE