Search for dissertations about: "Domain tree"

Showing result 1 - 5 of 57 swedish dissertations containing the words Domain tree.

  1. 1. Probabilistic Modelling of Domain and Gene Evolution

    Author : Sayyed Auwn Muhammad; Jens Lagergren; Bastien Boussau; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Phylogenetics; Phylogenomics; Evolution; Domain Evolution; Gene tree; Domain tree; Bayesian Inference; Markov Chain Monte Carlo; Homology Inference; Gene families; C2H2 Zinc-Finger; Reelin Protein; Computer Science; Datalogi;

    Abstract : Phylogenetic inference relies heavily on statistical models that have been extended and refined over the past years into complex hierarchical models to capture the intricacies of evolutionary processes. The wealth of information in the form of fully sequenced genomes has led to the development of methods that are used to reconstruct the gene and species evolutionary histories in greater and more accurate detail. READ MORE

  2. 2. The relationship between orthology, protein domain architecture and protein function

    Author : Kristoffer Forslund; Erik Sonnhammer; Cristina Al-Khalili Szigyarto; Sarah Teichmann; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; homology; orthology; paralogy; gene duplications; protein function prediction; low-complexity regions; protein domains; domain architecture evolution; introns; intron position conservation; orthology conjecture; domain grammar hypothesis; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

    Abstract : Lacking experimental data, protein function is often predicted from evolutionary and protein structure theory. Under the 'domain grammar' hypothesis the function of a protein follows from the domains it encodes. READ MORE

  3. 3. Formal Verification of Tree Ensembles in Safety-Critical Applications

    Author : John Törnblom; Simin Nadjm-Tehrani; Ingemar Söderquist; Joao Marques-Silva; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Formal verification; Machine learning; Tree ensembles;

    Abstract : In the presence of data and computational resources, machine learning can be used to synthesize software automatically. For example, machines are now capable of learning complicated pattern recognition tasks and sophisticated decision policies, two key capabilities in autonomous cyber-physical systems. READ MORE

  4. 4. Orthology and protein domain architecture evolution

    Author : Volker Hollich; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A major factor behind protein evolution is the ability of proteins to evolve new domain architectures that encode new functions. Protein domains are widely considered to constitute the "atoms" of protein chains, acting as building blocks of proteins as well as evolutionary units. READ MORE

  5. 5. Domain rearrangement and creation in protein evolution

    Author : Diana Ekman; Arne Elofsson; Christine Orengo; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioinformatics; Bioinformatik; Biochemistry; biokemi;

    Abstract : Proteins are composed of domains, recurrent protein fragments with distinct structure, function and evolutionary history. Some domains exist only as single domain proteins, however, a majority of them are also combined with other domains. READ MORE