Search for dissertations about: "Dynamic positron emission tomography"

Showing result 1 - 5 of 19 swedish dissertations containing the words Dynamic positron emission tomography.

2. 1. Towards Clinical Implementation of Dynamic Positron Emission Tomography in Neurodegenerative Diseases

   Author : My Jonasson; Mark Lubberink; Lieuwe Appel; Jens Sörensen; Michel Koole; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Positron emission tomography; PET; Molecular imaging; Quantification; Kinetic modelling; Parametric images; Alzheimer’s disease; Parkinson’s disease; Radiology; Radiologi;

   Abstract : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders worldwide. Positron emission tomography (PET), together with suitable biomarkers, can aid in the clin-ical evaluation as well as in research investigations of these diseases. READ MORE

4. 2. Quantitative methods for tumor imaging with dynamic PET

   Author : Ida Häggström; Anne Larsson; Mikael Karlsson; Lennart Johansson; Jens Sörensen; Magnus Dahlbom; Umeå universitet; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Dynamic positron emission tomography; PET; tumor imaging; compartment modeling; Monte Carlo; radiofysik; radiation physics;

   Abstract : There is always a need and drive to improve modern cancer care. Dynamic positron emission tomography (PET) offers the advantage of in vivo functional imaging, combined with the ability to follow the physiological processes over time. READ MORE

5. 3. Blood-Brain Barrier Transport : Investigation of Active Efflux using Positron Emission Tomography and Modelling Studies

   Author : Stina Syvänen; Margareta Hammarlund-Udenaes; Mats Bergström; Gunnar Blomquist; Jashvant Unadkat; Uppsala universitet; []
   Keywords : Pharmaceutical biosciences; pharmacokinetics; P-glycoprotein; blood-brain barrier; modelling; PET; active efflux; species differences; [11C]verapamil; drug development; Farmaceutisk biovetenskap;

   Abstract : This thesis examines the transport of exogenous molecules across the blood-brain barrier (BBB), focusing on active efflux, using positron emission tomography (PET), computer simulation and modelling. P-glycoprotein (P-gp) inhibition was studied using [11C]verapamil and [11C]hydroxyurea was investigated as a new marker for active efflux transport. READ MORE

6. 4. Regional Lung Kinetics of Ventilator-Induced Lung Injury and Protective-Ventilation Strategies Studied by Dynamic Positron Emission Tomography

   Author : João Batista Borges; Anders Larsson; Giacomo Bellani; Uppsala universitet; []
   Keywords : [18F]fluoro-2-deoxy-D-glucose; positron emission tomography; acute pulmonary inflammation; acute respiratory distress syndrome; mechanical ventilation; ventilator-induced lung injury;

   Abstract : Mechanical ventilation in itself can harm the lung and cause ventilator-induced lung injury (VILI), which can induce or aggravate acute respiratory distress syndrome (ARDS). Much debate remains over pivotal concepts regarding the pathophysiology of VILI, especially about the precise contribution, kinetics, and primary role of potential VILI mechanisms. READ MORE

7. 5. Amyloid imaging in Alzheimer’s disease and mild cognitive impairment by positron emission tomography

   Author : Anton Forsberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Effectiveness of future treatment strategies in Alzheimer s disease (AD) will rely on early detection of disease and the possibility to clearly evaluate their effects. The findings presented in this thesis concerns both early in vivo detection of amyloid deposition in the brains of patients at risk of developing AD and the longitudinal changes of pathological and functional parameters in patients with AD. READ MORE