Search for dissertations about: "EC 50"

Showing result 1 - 5 of 15 swedish dissertations containing the words EC 50.

  1. 1. In Vitro – In Vivo Correlation of Injectable Lipid Formulations

    University dissertation from Hospital Pharmacy, University Hospital, Malmö, Sweden and Department of Food Technology, Engineering and Nutrition, Lund University, Sweden

    Author : Lars Söderberg; Lunds universitet.; Lund University.; [2008]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; EC 50; erythrocyte; human plasma; lipid injectable formulation; IVIVC; fatty acid; in vitro release; Peripheral nerve block; neurolytic; structure-activity;

    Abstract : In order to develop new pharmaceuticals, to optimize pharmacotherapy and secure patient safety, documentation of the properties of pharmaceutical formulations is a most important process. A significant practical problem associated with pre-clinical evaluation of lipophilic substances with pharmacological properties is their low aqueous solubility. READ MORE

  2. 2. Mechanisms of endothelial cell dysfunction in Wegener´s granulomatosis

    University dissertation from Stockholm : Karolinska Institutet, Department of Laboratory Medicine

    Author : Carolina Holmén; Karolinska Institutet.; Karolinska Institutet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wegener´s granulomatosis; vasculitis; anti-endothelial cell antibody; circulating endothelial cell; vascular adhesion protein 1; MHC class-I related chain A;

    Abstract : Vasculitides are a heterogeneous group of disorders that share a common feature of blood vessel inflammation. A major cell type of the blood vessel affected is the endothelial cell (EC). READ MORE

  3. 3. Hereditary factors in endometrial cancer

    University dissertation from Stockholm : Karolinska Institutet, Dept of Women's and Children's Health

    Author : Gerasimos Tzortzatos; Karolinska Institutet.; Karolinska Institutet.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Endometrial carcinoma (EC) is the most common gynecological malignancy in Sweden and accounts for about 6 % of all female malignancies. The risk of EC increases with age and the majority of cases are diagnosed between age 50 and 60. Ninety percent of cases occur in women older than age 50. READ MORE

  4. 4. Carbonaceous Aerosol in Europe - out of the woods and into the blue?

    University dissertation from Göteborg : University of Gothenburg

    Author : Jan Robert Bergström; Göteborgs universitet.; Gothenburg University.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organic aerosol; elemental carbon; chemical transport modelling; residential wood combustion; biotic stress induced emissions; source apportionment; EMEP MSC-W model;

    Abstract : Particulate matter (PM) in the atmosphere influences weather and climate and may have important health impacts. Regional scale chemical transport modelling aims to describe the composition of particulate matter, to track different sources, estimate their relative importance, and to give realistic predictions of responses to changes in emissions and atmospheric conditions. READ MORE

  5. 5. Predictive testing for contact allergy : comparison of some guinea pig and mouse protocols including dose-response designs

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine

    Author : Helen Wahlkvist; Karolinska Institutet.; Karolinska Institutet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; contact allergens; contact allergy; cumulative contact enhancement test; dose-response; evaluation; Freund s complete adjuvant test; guinea pig maximization test; local lymph node assay; mouse ear swelling test; patch test; predictive testing; statistical analysis;

    Abstract : Contact allergy (delayed hypersensitivity) may develop as a result of skin exposure to contact allergens (haptens) and can lead to allergic contact dermatitis. The purpose of this study was to evaluate some predictive animal test methods for contact allergens. READ MORE