Search for dissertations about: "EGFR"

Showing result 1 - 5 of 122 swedish dissertations containing the word EGFR.

  1. 1. Nasopharyngeal carcinoma: past, present and future directions

    Author : Zahra Taheri-Kadkhoda; Göteborgs universitet.; Gothenburg University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nasopharyngeal carcinoma; radiotherapy; side effects; 3DCRT; Intracavitary brachytherapy; IMRT; IMPT; LMP1; EGFR.; radiotherapy; side effects; 3DCRT; Intracavitary brachytherapy; IMRT; IMPT; LMP1; EGFR;

    Abstract : Nasopharyngeal carcinoma (NPC) is a rare disease in Sweden. The purpose of this thesis was to investigate the clinicopathological manifestations of the disease and its treatment outcomes in a cohort of Swedish NPC patients to identify key features for future improvements in patient care. READ MORE

  2. 2. EGFR- and HER2-Binding Affibody Molecules Cellular studies of monomeric, dimeric and bispecific ligands

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Lina Ekerljung; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EGFR; HER2; Affibody molecule; cell signaling; receptor dimerization; Biomedical Radiation Science; Biomedicinsk strålningsvetenskap;

    Abstract : Abnormal expression and signaling of the ErbB receptors is associated with the development and progression of several forms of cancer. In this thesis, new ErbB-targeting affibody molecules are evaluated regarding their cellular effects in vitro. READ MORE

  3. 3. Oesophageal Cancer – Novel Targets for Therapy With focus on Hsp90, EGFR, LRIG, microtubule and telomerase

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Xuping Wu; Uppsala universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hsp90; EGFR; LRIG; microtubule; telomerase; oesophageal cancer; imetelstat; DNA double-strand break; 17-AAG; radiation; prognosis; radiosensitisation; microtubule targeting agents; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Oncology; Onkologi;

    Abstract : Oesophageal cancer is a malignant and aggressive disease with very poor survival. The aim of this thesis was to evaluate novel therapeutic targets in oesophageal cancer.In paper I, Hsp90 was expressed in all 81 oesophageal cancer tissues and also in nine oesophageal cancer cell lines. READ MORE

  4. 4. Androgen controlled regulatory systems in prostate cancer potential new therapeutic targets and prognostic markers

    University dissertation from Umeå : Medicinsk biovetenskap

    Author : Peter Hammarsten; Umeå universitet.; [2008]
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; prostate cancer; angiogenesis; human biopsy; androgen ablation; castration; prognostic marker; prognostic factor; growth control; VEGF; vascular endothelial growth factor; EGFR; epidermal growth factor receptor; pEGFR; phosphorylated EGFR; phosphorylated epidermal growth factor receptor; VETERINARY MEDICINE Pathology; VETERINÄRMEDICIN Patologi;

    Abstract : BACKGROUND: Prostate cancer is by far the most common cancer among Swedish men. Some patients have an aggressive lethal disease, but the majority of affected men have long expected survival. Unfortunately, the diagnostic tools available are insufficient in predicting disease aggressiveness. Novel prognostic markers are therefore urgently needed. READ MORE

  5. 5. EGFR and HER2 Targeting for Radionuclide-Based Imaging and Therapy Preclinical Studies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erika Nordberg; Uppsala universitet.; [2008]
    Keywords : Biomedicine; EGFR; HER2; affibody molecule; tumour targeting; 125I; 111In; Biomedicin;

    Abstract : The optimal way to detect and treat cancer is to target cancer cells exclusively without affecting the surrounding tissue. One promising approach is to use radiolabelled molecules to target receptors that are overexpressed in cancer cells. READ MORE