Search for dissertations about: "ESCRT complex"

Found 4 swedish dissertations containing the words ESCRT complex.

  2. 1. Non-canonical ATG8 conjugation in ESCRT-driven membrane remodeling processes

    Author : Anastasia Knyazeva; Yao-Wen Wu; Richard Lundmark; Sascha Martens; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ATG8 conjugation; Endosomal Sorting Complex Required for Transport; membrane remodeling; chemical genetics;

    Abstract : ATG8 family proteins have the unique ability to conjugate to membrane lipids. Initially identified as a hallmark of autophagy, ATG8 lipidation is emerging as an important regulator of a growing list of non-degradative cellular functions. READ MORE

  4. 2. The release of histone proteins from cells via extracellular vesicles

    Author : Uma Muthukrishnan; Jonathan Gilthorpe; Miles Trupp; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Histone; extracellular vesicles; exosomes; extracellular histones extracellular DNA; cellular stress; proteomics; ESCRT complex; Lrrn1; mid-hindbrain organizer; ovarian cancer; ascites;

    Abstract : Histones are chromatin-associated proteins localized to the nucleus. However, extracellular histones are present in biofluids from healthy individuals and become elevated under disease conditions, such as neurodegeneration and cancer. READ MORE

  5. 3. Structural Details of Human Aquaporin Regulation : Three stories of three aquaporins

    Author : Veronika Nesverova; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; aquaporin; membrane proteins; protein trafficking; water channel; aquaporin 0; aquaporin 5; aquaporin 2; cryo-EM; protein phosphorylation; protein-protein interaction; aquaporin regulation; aquaporins;

    Abstract : Every cell is surrounded by a thin plasma membrane, protecting it from its surrounding. Specialized protein channels and transporters are embedded in this membrane, ensuring selective transport of molecules in and out of the cells. To maintain optimal hydration, water channels called aquaporins (AQPs) are present in every cell of our body. READ MORE

  6. 4. Bacterial genotoxins : an interface between infection and cancer biology

    Author : Laura Levi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Infections contribute to the development of more than 20% of all malignancies in humans. While strong evidence exists for a number of virus-associated cancers, the role of bacterial infections is still poorly appreciated although there are evidences that link chronic bacterial infections to increased risk of certain tumors. READ MORE