Search for dissertations about: "Elevated plus-maze"

Showing result 1 - 5 of 12 swedish dissertations containing the words Elevated plus-maze.

  2. 1. Nicotine sensitization and the effects of extended withdrawal - behavioral, neurochemical and electrophysiological studies in the rat

    Author : Julia Morud; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abstinence; Dopamine; Elevated plus-maze; GABA; Inhibitory control; Nicotine; Nucleus accumbens; Sensitization;

    Abstract : Tobacco use is one of the primary factors for global burden of disease and often results in life-long nicotine addiction, only a small percentage users are able to maintain cessation. The life-long addiction together with a high relapse risk might be connected to drug-induced altered neural circuits. READ MORE

  4. 2. Nicotine sensitization and loss of inhibitory control. Role of serotonin

    Author : Peter Olausson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nicotine; Amphetamine; Locomotor activity; Inhibitory control; Dopamine; Serotonin; Sensitization; Nucleus accumbens; Elevated plus-maze;

    Abstract : Drug dependence is a devastating disorder present in all parts of the world. It is manifested by craving and a general loss of control over the drug intake and the life situation, ultimately leading to compulsive use of the addictive drug at the expense of normal behavioral patterns. READ MORE

  5. 3. Maternal Separation in Rats : An Experimental Model for Long-Term Effects of Early Life Experiences on Neurochemistry, Voluntary Ethanol Intake and Exploration and Risk Assessment Behavior

    Author : Erika Roman; Ingrid Nylander; J. Dee Higley; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical pharmacology; Handling; Maternal Deprivation; Environment; Opioids; Dopamine; Alcohol; Stress; Concentric Square Field; Open Field; Elevated Plus-maze; Farmaceutisk farmakologi; Pharmaceutical pharmacology; Farmaceutisk farmakologi;

    Abstract : The period of early life is important for the development of individual brain function and behavior. Human studies have shown altered vulnerability to develop psychopathology and/or excessive drug intake, possibly leading to dependence, as a consequence of early life experiences. READ MORE

  6. 4. Influenza A virus infection and NMDA receptor function : a behavioral and molecular study of relevance for schizophrenia

    Author : Simret Beraki; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Schizophrenia; Influenza A virus; NMDA receptor; glutamate; cognition; learning; memory; hippocampus; water maze; mice; emotional; social interaction; gene expression; brain; behavior; phencyclidine; elevated plus-maze;

    Abstract : Schizophrenia is a neuropsychiatric disorder characterized by positive and negative symptoms, as well as cognitive dysfunctions. There is no single cause of schizophrenia, instead complex combinations of genetic and environmental factors may contribute to the disorder, including exposure to viral infections or other environmental insults during early life. READ MORE

  7. 5. Neonatal Exposure to Anaesthesia and Adjuvants : Acute Effects on Cerebral Apoptosis and Neuroproteins, and Late  Behavioural Aberrations in Mice

    Author : Emma Pontén; Anders Fredriksson; Torsten Gordh; Steen Henneberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anaesthesia; neonatal; apoptosis; bahaviour; clonidine; ketamine; propofol; theophyllamine; Medicin; Medicine;

    Abstract : During a finite developmental phase – the brain growth spurt – the brain grows and matures at an accelerated rate. During this period the brain is more sensitive to harmful substances such as ethanol and environmental toxins than before or after. READ MORE