Search for dissertations about: "En1"

Found 4 swedish dissertations containing the word En1.

  2. 1. The Complex Genetics behind Neurodegeneration and Susceptibility to Parkinson’s disease

    Author : Michael Jewett; Translationell Neurogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s Disease; α-synuclein; Dopaminergic Neurons; Susceptibility; GSTA4; Vra1; rAAV; 6-OHDA; En1; Linkage analysis; Congenic strains; Axonal swellings; QTL; Risk factors; Neuroprotection; Astrocytes;

    Abstract : Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest. READ MORE

  4. 2. Immunogenetics of Parkinson's disease: Translational studies from rodents to humans

    Author : Itzia Jimenez; Translationell Neurogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genetics; inflammation; α-synuclein; dopaminergic neurons; MHCII; Mhc2ta; Vra4; PFFs; microglia;

    Abstract : Parkinson's disease (PD) is a complex neurodegenerative disease, characterized by a progressive lossof dopaminergic neurons (DN) in the substantia nigra (SN) that innervate the striatum (ST) and pathologicalaccumulation of alpha-synuclein (αsyn) protein in aggregates called Lewy bodies (LB) and Lewy neurites(LN). As a complex disease, PD presents a genetically heterogeneous origin. READ MORE

  5. 3. Simulation of mechanical joining for automotive applications

    Author : Johannes Gårdstam; Anders Eriksson; Kjell Simonsson; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Other materials science; Övrig teknisk materialvetenskap;

    Abstract : Regarding the use of material, modern lightweight car bodies are becoming more and more complex than previous constructions. The materials nowadays are used for a more specific field of application and more high strength steels are used and also other materials like aluminium, stainless steel, reinforced polymers are used more frequent. READ MORE

  6. 4. Stainless Steel Corrugated Web Girders for Composite Road Bridges: Concept Evaluation and Flange Buckling Resistance

    Author : Fatima Hlal; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Investment cost; Genetic algorithm; Duplex stainless steel; LCC; Corrugated web; Flange buckling resistance; Optimization; Composite bridges; LCA; Road bridges;

    Abstract : Achieving a sustainable bridge design requires careful consideration of economic viability and environmental impact over the entire lifespan of the structure. While stainless steel is recognized for its excellent life cycle performance, its high cost prevents it from being used to a larger extent in bridges. READ MORE