Search for dissertations about: "Endogenous glucose production"
Showing result 1 - 5 of 22 swedish dissertations containing the words Endogenous glucose production.
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1. Perioperative glucose control
Abstract : Trauma or surgery elicit a physiological stress response, which among others induces insulin resistance. It could be described as a state where the biological response to a given dose of insulin is reduced, and is associated with an altered glucose metabolism, as well as a disturbed lipid and protein metabolism and dysfunctional immune, inflammatory and coagulation systems. READ MORE
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2. Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity
Abstract : Type 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. READ MORE
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3. Mechanism-Based Modelling of Clinical and Preclinical Studies of Glucose Homeostasis
Abstract : Glucose is an important nutrient and energy source in the body. However, too high concentration in the blood is harmful and may lead to several complications developing over time. It was estimated that 5 million people in the world died from complications related to diabetes during 2015. READ MORE
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4. Long-acting insulin analogs in type 1 diabetes : effects on metabolic control, endogenous insulin production and the GH-IGF-axis
Abstract : The treatment goal in type 1 diabetes is to achieve near-normal glycemia. Despite of the advancements of subcutaneous insulin therapy and glucose monitoring, metabolic control is not fully normalized and secondary endocrine disturbances in the growth-hormone (GH) - Insulin-like Growth Factor (IGF)-axis are important for the deterioration of metabolic control, particularly in children at puberty. READ MORE
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5. Insulin-like growth factor-I deficiency, insulin sensitivity, and glucose metabolism
Abstract : In children and adolescents, growth hormone (GH) and insulin-like growth factor-I (IGF-I) act in concert to stimulate linear growth; however, the effects on glucose metabolism are in opposition. GH increases insulin resistance by lipolysis. READ MORE