Search for dissertations about: "Erik Simonsson"

Found 3 swedish dissertations containing the words Erik Simonsson.

  2. 1. On Cholecystokinin and Phospholipase A2 in Insulin Secretion - an Experimental Study With Reference to the Development of Diabetes

    Author : Erik Simonsson; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Insulin Resistance; Islet; Beta-cell; Insulin Secretion; Ca2 -Dependency; Intracellular Signalling; Phospholipase A2; Cholecystokinin; Non-glucose Secretagogues; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : In view of unsolved issues regarding cellular events underlying the adaptation of insulin secretion to insulin resistance, together with the observation that insulin secretion induced by the gastrointestinal hormone and neuropeptide cholecystokinin (CCK) is not solely explained by phospholipase C-protein kinase C (PLC-PKC) pathway activation, this study aimed at delineate mechanisms responsible for the hyperinsulinemia in insulin resistance, with particular attention paid to the action of glucose vs. non-glucose secretagogues, such as CCK. READ MORE

  4. 2. Modelling of fatigue crack propagation in Inconel 718 under hold time conditions

    Author : Erik Lundström; Kjell Simonsson; Tomas Månsson; David Gustafsson; Johan Moverare; Martin Hughes; Linköpings universitet; []
    Keywords : ;

    Abstract : In this thesis an investigation and modelling of the fatigue crack propagation in the nickel based superalloy Inconel 718, with a special emphasis on the effect of hold times, is presented. The modelling work has been concentrated on describing the hold time fatigue crack propagation by using the concept of a damaged zone in front of the crack tip, which is believed to have a lowered resistance against crack propagation. READ MORE

  5. 3. High Temperature Fatigue Crack Growth in a Ni-based Superalloy : Modelling Including the Interaction of Dwell Times

    Author : Erik Storgärds; Kjell Simonsson; Johan Moverare; Tomas Månsson; Bo Alfredsson; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Safe life of gas turbines is always of major concern for manufacturers in order to ensure passenger safety and stable continuous power output. An increasing amount of resources have been put into research and development to assure that all safety aspects are covered in the design of new turbines and to ensure that enough frequent service intervals are scheduled to avoid complications. READ MORE