Search for dissertations about: "Experimental Serology"

Showing result 1 - 5 of 25 swedish dissertations containing the words Experimental Serology.

2. 1. Costimulation Blockade in Experimental Transplantation

   Author : Helene Malm; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; serologi; Immunologi; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; graft survival; anti-CD40L; CTLA4Ig; anti-LFA-1; costimulation blockade;

   Abstract : Transplantation is the only cure for end-stage organ failure. With the transplantation follows the need for continuous treatment with immunosuppressive agents for as long as the graft functions, which entails major side effects. Less toxic treatments are therefore in great demand. Preferably, the treatment should also be limited in time. READ MORE

4. 2. Lung Transplantation: Clinical and experimental studies

   Author : Leif Eriksson; allergologi och palliativ medicin Lungmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Respiratory system; Follow up Studies; Vascular Resistance; Intensive Care; Induced; Hypothermia; Swine; Extracorporeal Circulation; Lung Transplantation; Organ Preservation; Andningsorganen; Immunology; serology; transplantation; Immunologi; serologi;

   Abstract : During the past 15 years lung transplantation has been established as a therapeutic option for patients with end-stage pulmonary disease. The results have improved over time and some transplantation centers now show 1-year survival rates above 80%. READ MORE

5. 3. Immunoregulation in an experimental model of allergic asthma

   Author : Magnus Korsgren; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; macrophage migration inhibitory factor; eosinophils; gd T cells; NK1.1 T cells; natural killer cells; immunoglobulins; B cells; innate immunity; allergic airway inflammation; immediate hypersensitivity; Physiology; Fysiologi; Immunology; serology; transplantation; Immunologi; serologi;

   Abstract : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. READ MORE

6. 4. Experimental modulation and suppression of anti-allograft immune response

   Author : Öyvind Östraat; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; linomide; leflunomide; cyclophosphamide; mycophenolate mofetil; azathioprine; thalidomide; cyclosporin A; ciprofloxacin; flow cytometry; production; IL-2; Rat cardiac transplantation; allograft; Immunology; serology; transplantation; Immunologi; serologi;

   Abstract : Abstract The objective of this investigation was to characterise the immunomodulatory or immunosuppressive effects of single drug treatment and the potential synergistic or additive effects of combined treatment with the focus on ciprofloxacin, thalidomide, mycophenolate mofetil, azathioprine, cyclophosphamide or leflunomide added to cyclosporin A (CyA). A rat cardiac transplant model was used to study graft survival and the influence on lymphocytes was evaluated by in vitro tests. READ MORE

7. 5. Specifity and genetic control of B cell reactivity in experimental arthritis

   Author : Patrik Wernhoff; Immunologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serologi; transplantation; Genetics; cytogenetics; Genetik; cytogenetik; Immunologi; Autoimmunity B-cell response Epitope Genetics Linkage Analysis; Immunology; serology;

   Abstract : Collagen-induced arthritis (CIA) and pristane-induced arthritis (PIA) are animal models for human rheumatoid arthritis (RA), and can be induced in susceptible mouse and rat strains. CIA is induced by immunization of type II collagen (CII), a cartilage specific protein together with Freund’s adjuvant. READ MORE