Search for dissertations about: "Fas CD95"

Showing result 1 - 5 of 7 swedish dissertations containing the words Fas CD95.

  2. 1. Apoptosis Regulation in Multiple Myeloma

    Author : Lina Dimberg; Helena Jernberg Wiklund; Kenneth Nilsson; Marie Arsenian Henriksson; Uppsala universitet; []
    Keywords : Biomedicine; multiple myeloma; apoptosis; survival; IFN; Stat1; Stat3; IGF-I; RTK inhibitor; PPP; IAP; Fas CD95; dexamethasone; Biomedicin;

    Abstract : Multiple myeloma (MM) is a virtually incurable B cell malignancy of the bone marrow. One important part of tumor progression and an obstacle for successful therapy is resistance to apoptosis. To combat this resistance, the mechanisms of apoptosis and survival in MM must be better defined. READ MORE

  4. 2. Thiol redox state in apoptosis : physiological and toxicant modulation

    Author : Stefan Nobel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Apoptosis is a physiological type of cell death used to regulate the number of cells during development and in adult organs. However, apoptosis can also be inappropriately activated or inhibited under pathological conditions. One of the critical mechanisms of apoptosis is the activity of cysteine proteases belonging to the caspase family. READ MORE

  5. 3. The contribution of epidermal apoptosis to the clinical outcome of Leishmania aethiopica induced cutaneous Leishmaniasis, and its laboratory diagnosis using low cost culture media

    Author : Geremew Tasew Guma; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Cutaneous Leishmaniasis (CL) induced by Leishmania aethiopica has two clinical manifestations: ulcerating, self-healing CL and non-ulcerating, non-healing CL. The grossly disfiguring multiple nodules on the face and exterior surface of limbs during non-ulcerative CL are sometimes misdiagnosed as other skin infections. READ MORE

  6. 4. Prediction of side effects from anticancer treatment with the purpose of increasing quality of life

    Author : Delmy Oliva; Freddi Lewin; Charlotta Dabrosin; Lena Sharp; Lasse D Jensen; Eva Brun; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Cancer and its treatments can cause a variety of symptoms. Some of these symptoms are related to the disease and others are seen as a consequence of the treatment. Since patients experience side effects to different degrees despite undergoing the same treatment, it is hypothesized that there is a genetic factor. READ MORE

  7. 5. Immunogenicity of and apoptosis modulation by Epstein-Barr virus (EBV)-encoded latent membrane protein-1 (LMP1) : implications for nasopharyngeal carcinoma

    Author : Xiangning Zhang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus which infects more than 90% of individuals in the population, and has been shown to be associated with a variety of human tumors. The viral genome encodes a number of transforming proteins which enable the virus to efficiently immortalize B lymphocyte and also transform cells of other types. READ MORE