Search for dissertations about: "Fed-batch"
Showing result 1 - 5 of 69 swedish dissertations containing the word Fed-batch.
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1. Perturbation-based Control of Industrial Fed-batch Bioprocesses
Abstract : The topic of this thesis is bioprocess control, more specifically control of industrial-scale microbial fed-batch bioprocesses. Its focus is therefore on methods which are easy to implement in an industrial setting, which gives certain limitations on sensors, actuators and control systems. READ MORE
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2. Development of a protein-free fed-batch process for NS0 cells: studies on regulation of proliferation
Abstract : The overall objective of this study was to investigate how NS0 cell proliferation is regulated in protein-free media. The hypothesis was that during the adaptation to growth factor-free media, animal cell lines start to produce their own autocrine growth factors to support proliferation, and after some time in a culture the effects of these factors are lost which results in cessation of proliferation. READ MORE
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3. Large-scale Bioreactor Phenomena and Characteristics; Effects on E.coli fed batch fermentations on 30m3 scale
Abstract : Due to economical and practical limitations the fluiddynamics and mass transport properties are less optimal inlarge-scale bioreactors compared to lab-scale bioreactors. Incombination with the microbial reaction rates this creates amuch more dynamic environment for cells cultivated inlarge-scale bioreactors compared to lab-scale bioreactors. READ MORE
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4. Probing Control : Analysis and Design with Application to Fed-Batch Bioreactors
Abstract : In most control problems the objective is to control the output at a desired value in spite of disturbances. In some cases, the best setpoint is not known a priori and it should be found online to optimize the process performance. This thesis examines a probing strategy that can be applied for this class of problems. READ MORE
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5. Performance and Scale-up of Escherichia coli Fed-batch Processes- Oxygenation of the Human Growth Hormone Process
Abstract : .... READ MORE