Search for dissertations about: "Fedor Nikulenkov"

Found 1 swedish dissertation containing the words Fedor Nikulenkov.

2. 1. Modulation of p53's transcriptional function by small molecules

   Author : Fedor Nikulenkov; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : p53 tumour suppressor is a transcriptional factor which induces apoptosis or growth arrest in response to stress thus eliminating damaged cells. p53 function is frequently abrogated in tumours either via inactivation mutations in the TP53 gene or by elevated activity of p53 negative regulators HDM2 and HDMX. READ MORE