Search for dissertations about: "Fitness effects"

Showing result 1 - 5 of 238 swedish dissertations containing the words Fitness effects.

2. 1. Finding fitness : empirical and theoretical explorations of inferring fitness effects from population-level SNP data

   Author : Bea Angelica Andersson; Xiao-Ru Wang; Åke Brännström; Tanja Slotte; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; distribution of fitness effects; site frequency spectra; missing data filtering; downsampling; imputation; sample size; population structure; inbreeding; selfing; homozygosity; Arabidopsis; Pinus; DFE-alpha; SLiM; population genomics; adaptation; biology; biologi; evolutionär genetik; evolutionary genetics; populationsbiologi; Population Biology; molekylärbiologi; Molecular Biology; Genetics; genetik;

   Abstract : The distribution of fitness effects (DFE) describes the likelihood that a new mutation has a specific effect on the fitness of an individual in a given population. The shape of the DFE is a result of several factors such as population size, mating system and selective environment, and can in turn influence the evolutionary potential of a species. READ MORE

4. 2. Experimental Evolution : and Fitness Effects of Mutations

   Author : Anna Knöppel; Dan I Andersson; Stanley Maloy; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Experimental evolution; Fitness effects; mutations; S20; fis; ribosome; horizontal gene transfer; adaptation; synonymous mutations; Mikrobiologi; Microbiology;

   Abstract : Bacteria have small, streamlined genomes and evolve rapidly. Their large population sizes allow selection to be the main driver of evolution. With advances in sequencing technologies and precise methods for genetic engineering, many bacteria are excellent models for studying elementary questions in evolutionary biology. READ MORE

5. 3. Bacterial Resistance to Antimicrobial Peptides : Rates, Mechanisms and Fitness Effects

   Author : Maria Pränting; Dan Andersson; Ian Chopra; Uppsala universitet; []
   Keywords : antimicrobial peptides; antibiotic resistance; fitness cost; bacterial evolution; small colony variants; cyclotides; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology; Mikrobiologi; Microbiology;

   Abstract : The rapid emergence of bacterial resistance to antibiotics has necessitated the development of alternative treatment strategies. Antimicrobial peptides (AMPs) are important immune system components that kill microbes rapidly and have broad activity-spectra, making them promising leads for new pharmaceuticals. READ MORE

6. 4. Removal and Replacement of Ribosomal Proteins : Effects on Bacterial Fitness and Ribosome Function

   Author : Christina Tobin; Dan I. Andersson; Richard Buckingham; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ribosome; protein synthesis; ribosomal proteins; translation initiation; ribosome biogenesis; fitness costs; compensatory evolution; horizontal gene transfer; Microbiology; Mikrobiologi; Biochemistry; Biokemi; Mikrobiologi; Microbiology;

   Abstract : Protein synthesis is a complex process performed by sophisticated cellular particles known as ribosomes. Although RNA constitutes the major structural and functional component, ribosomes from all kingdoms contain an extensive array of proteins with largely undefined functional roles. READ MORE

7. 5. Injury Prevention in Youth Football Players : Training Effects and Programme Implementation

   Author : Hanna Lindblom; Martin Hägglund; Markus Waldén; Siw Carlfjord; Keith Stokes; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Background With 17–35% of all 14-year-olds in Sweden being active in football, injuries do occur, most frequently during match play. Based on knowledge of injury mechanisms and risk factors, different injury prevention exercise programmes (IPEPs) have been developed. READ MORE