Search for dissertations about: "FusB"
Found 4 swedish dissertations containing the word FusB.
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1. Life will find a way : Structural and evolutionary insights into FusB and HisA
Abstract : How do microbes adapt to challenges from the environment? In this thesis, two distinct cases were examined through structural and biochemical methods. In the first, we followed a real-time protein evolution of HisA to a novel function. The second case was fusidic acid (FA) resistance mediated by the protein FusB in Staphylococcus aureus. READ MORE
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2. Characterizing Elongation of Protein Synthesis and Fusidic Acid Resistance in Bacteria
Abstract : Protein synthesis is a highly complex process executed by the ribosome in coordination with mRNA, tRNAs and translational protein factors. Several antibiotics are known to inhibit bacterial protein synthesis by either targeting the ribosome or the proteins factors involved in translation. READ MORE
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3. On Fusidic Acid Resistance in Staphylococcus Aureus
Abstract : Controlling bacterial infections with antibiotics is central to modern health care. However, increasing bacterial resistance to antibiotics threatens effective therapy. This thesis concerns the use of the antibiotic fusidic acid, and novel analogues of fusidic acid, to treat topical infections caused by the bacterial pathogen Staphylococcu aureus. READ MORE
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4. Translational accuracy, ribozyme efficiency and NAD metabolism in Escherichia coli
Abstract : Interactions between the translational machinery and mRNA in Escherichia coli have been studied. In the first section nonsense codon readthrough and changed translational reading frame were measured in different growth phases. READ MORE