Search for dissertations about: "G André"
Showing result 1 - 5 of 25 swedish dissertations containing the words G André.
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1. Intracellular unbound drug concentrations : Methodology and application for understanding cellular drug exposure
Abstract : Most known drug targets and metabolizing enzymes are located inside cells. Interactions with these proteins are determined by intracellular unbound drug concentrations. Assessing intracellular drug exposure is technically challenging, but essential for predicting pharmacokinetic, pharmacological, and toxicological profiles of new drugs. READ MORE
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2. Genetic Variability in Human Bone Phenotypes : The Vitamin D Receptor Gene and the Estrogen Receptor-α Cofactor RIZ Gene
Abstract : Important candidate genes to human bone phenotypes are those involved in the regulation of hormonal action, such as the vitamin D receptor (VDR) and the estrogen receptor-α (ERα) genes and their cofactors. RIZ1 is a specific ERα cofactor proved to strongly enhance the function of the ERα. READ MORE
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3. Characterization of secreted Giardia intestinalis cysteine proteases
Abstract : Giardia intestinalis, the causative agent of the diarrheal disease giardiasis, is a protozoan parasite that colonizes the upper small intestine of mammals, including humans. It can be divided into eight genotypes or assemblages (A through H) and only assemblage A and B are infective to humans. READ MORE
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4. Modelling and control of turbulent and transitional flows
Abstract : The dynamics of fluid motion can accurately be described by the Navier– Stokes equations. Manipulating these equations to reduce their complexity but preserving their main characteristics has always been a key research activity in the field of fluid mechanics. READ MORE
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5. The Uncemented Cup in Total Hip Arthroplasty : stability, Wear and Osteolysis
Abstract : Background: Artificial hip joint replacement has undergone tremendous development in the past 100 years. In the beginning, complications, such as infection and early loosening, were the rule rather than the exception. Today, complications of any sort are rare during the first decade after the operation. READ MORE