Search for dissertations about: "G-protein"
Showing result 21 - 25 of 250 swedish dissertations containing the word G-protein.
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21. Molecular Pharmacology and Structure Function Modelling of the Leukotriene B4 Receptor BLT1
Abstract : Leukotrienes are membrane derived bioactive lipids that play an important role in immune responses by initiating and maintaining the inflammatory responses. Leukotriene B4 (LTB4) released at the site of an inflammatory response attracts, activates and prolongs the life of leukocytes and lymphocytes. READ MORE
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22. Synthesis and Structure of Novel G-Protein Coupled Receptor Ligands
Abstract : A method based on h6-arenetricarbonylchromium chemistry has been developed for the synthesis of enantiopure 4-alkylated 3-(dipropylamino)chromans. The stereochemistry of these new serotonergic ligands was determined by a combination of X-ray crystallography, NMR spectroscopy and chemical correlation. READ MORE
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23. Cloning and characterization of neuropeptide Y receptors of the Y1 subfamily in mammals and fish
Abstract : Neuropeptide Y (NPY) is an abundant neurotransmitter in the nervous system and forms a family of evolutionarily related peptides together with peptide YY (PYY), pancreatic polypeptide (PP) and polypeptide Y (PY). These peptides are ligands to a family of receptors that mediate a wide range of physiological effects including stimulation of appetite. READ MORE
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24. Oxygen sensing in Caenorhabditis elegans
Abstract : Sufficient supply of oxygen (O2) to tissue is essential for survival of aerobicanimals. In mammals, there are constant homeostatic regulation mechanisms that act on different time scales to maintain optimal O2 delivery to tissues. The ability to detect and respond to acute oxygen shortages is indispensable to aerobic life. READ MORE
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25. The Role of Membrane Trafficking in G Protein-Coupled Receptor Regulation
Abstract : Movements of a receptor in the plasma membrane and within the cell influence receptor function and physiology. I have investigated the role of such movements, generally known as membrane trafficking, in G protein-coupled receptor regulation. READ MORE