Search for dissertations about: "GH receptor"

Showing result 16 - 20 of 54 swedish dissertations containing the words GH receptor.

  2. 16. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency

    Author : Edna J L Barbosa; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; growth hormone deficiency; hypopituitarism; growth hormone replacement therapy; prediction models; candidate gene approach; polymorphisms; body composition; growth hormone receptor; lipid metabolism; extracellular water; pharmacogenomics;

    Abstract : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. READ MORE

  4. 17. Presence of extrathyroidal TSH-receptor, with special reference to its role in neonatal regulation of lipolysis

    Author : Annika Janson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : adaptation; adipocytes; Graves disease; growth hormone; human; hyper thyroidism; infant; insulin; metabolism; TSHR stimulating antibodies; thyrotropin; TSH.;

    Abstract : At birth, the newborn child must utilize stored energy until lactation is established. The main source of energy is fat - that is, triglycerides stored in the white adipose tissue. This study deals with hormonal regulation of lipolysis in the neonatal period. READ MORE

  5. 18. Analysis of functional genetic polymorphisms in prostate cancer and type 2 diabetes : mucin 1 and growth hormone receptor

    Author : Rona J Strawbridge; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Prostate cancer and type 2 diabetes are complex diseases, the genetic and environmental basis of which are not well established. Epidimiology suggests a link between the two diseases, with type 2 diabetes redusing the risk of prostate cancer, and faily history of prostate cancer reducing the risk of type 2 diabetes. READ MORE

  6. 19. Regulation of insulin-like growth factor-II in human liver

    Author : Henrik von Horn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : IG17-II; IGF2; IGFBPs; liver; hepatoblastoma; GH; hypoxia;

    Abstract : Insulin-like growth factors-I and -II (IGF-I and -II) are mitogens in a number of cell types and also have insulin-like actions. IGF-II has an autocrine role in a variety of malignancies; and hypoglycemia is well documented in conditions associated with elevated IGF-II precursor forms in the circulation. READ MORE

  7. 20. Insulin and growth hormone : regulation of adipocyte metabolism during infancy and childhood

    Author : Ashraf Fawzy Kamel; Karolinska Institutet; Karolinska Institutet; []
    Keywords : human; rat; development; adipocytes; lipolysis; lipogenesis; glucose transport GLUT1; GLUT4; insulin; insulin receptor; growth hormone; growth hormone receptor microdialysis; obesity; Prader-Willi syndrome;

    Abstract : The aim of the present investigation was to investigate the role of insulin and growth (GH) in adipose tissue metabolism during development. Lipolysis and lipogenesis were studied in isolated adipocytes from humans and rats of various ages. READ MORE