Search for dissertations about: "Genetics of resistance genes"

Showing result 1 - 5 of 50 swedish dissertations containing the words Genetics of resistance genes.

  1. 1. Identification of novel antibiotic resistance genes through large-scale data analysis

    University dissertation from Chalmers University of Technology

    Author : Fanny Berglund; Chalmers tekniska högskola Göteborgs universitet.; Chalmers University of Technology University of Gothenburg.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metagenomics; hidden Markov model; carbapenemases; antibiotic resistance; big data;

    Abstract : Antibiotic resistance is increasing worldwide, and is considered a serious threat to public health by e.g. the World Health Organization. Antibiotic resistance genes are hypothesized to originate from harmless bacteria in and around us, from where they are horizontally transfered into human pathogens. READ MORE

  2. 2. Linkage maps in studies of genetic variation - examples from Beta vulgaris

    University dissertation from Department of Genetics, Lund University

    Author : Thomas Kraft; Lunds universitet.; Lund University.; [1999]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Genetics; cytogenetics; Beta vulgaris; Linkage maps; genetic variation; Genetik; cytogenetik;

    Abstract : Today, most studies of genetic variation utilise molecular markers, making it possible to detect variation at the DNA level. This has greatly facilitated studies of genetic variation in population and evolutionary genetics, systematics and transmission genetics. READ MORE

  3. 3. Type 2 Diabetes Genes Contributing to Insulin Secretion Defects

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Charlotte Granhall; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; exocytosis; GK rat; NIDDM1I; genetics; gene expression; quantitative trait analysis; Sorcs1; Adra2a; Endocrinology; diabetology; insulin secretion; diabetologi; secreting systems; Type 2 diabetes;

    Abstract : Type 2 diabetes is caused by a combination of environmental and inherited factors influencing the progression of insulin resistance and impaired insulin secretion leading to chronically elevated blood glucose levels. The aim of this thesis was to functionally and genetically characterise the species-conserved diabetes locus Niddm1i of the GK rat encoding hyperglycaemia and defect insulin secretion. READ MORE

  4. 4. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Marlen Adler; Uppsala universitet.; [2014]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carbapenem; antibiotic resistance; fitness cost; ESBLs; penicillin-binding proteins; gene amplification;

    Abstract : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. READ MORE

  5. 5. Development of molecular biology tools for the wine and beer yeast Dekkera bruxellensis

    University dissertation from Department of Biology, Lund University

    Author : Anna Schifferdecker; Lunds universitet.; Lund University.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Dekkera bruxellensis; non-conventional yeasts; genetic tools; chromosomes variability; glucose fermentation; genotype-phenotype paradigm; baking yeasts;

    Abstract : The non-conventional wine and beer yeast Dekkera bruxellensis is of great interest for the food industry and academic research. This Crabtree-positive yeast is a good ethanol producer and can compete the baker´s yeast Saccharomyces cerevisiae, in ethanol and pH tolerance and could be an even better organism for the biofuel production from alternative carbon sources. READ MORE