Search for dissertations about: "Genome rearrangement"

Showing result 1 - 5 of 22 swedish dissertations containing the words Genome rearrangement.

  2. 1. Studies of Genome Diversity in Bartonella Populations : A journey through cats, mice, men and lice

    Author : Hillevi Lina Lindroos; Siv G. E. Andersson; Richard Birtles; Uppsala universitet; []
    Keywords : Biology; Bartonella; genome content; genome rearrangement; gene expression; phage; microarray; PFGE; MLST; Biologi;

    Abstract : Bacteria of the genus Bartonella inhabit the red blood cells of many mammals, including humans, and are transmitted by blood-sucking arthropod vectors. Different species of Bartonella are associated with different mammalian host species, to which they have adapted and normally do not cause any symptoms. READ MORE

  4. 2. Genome dynamics and virulence in the human pathogen Candida glabrata

    Author : Khadija Mohamed Ahmad; Molekylär cellbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Pathogenic yeast; Candida glabrata; small chromosomes; Genome rearrangement; Haploid and diploid yeast; RNA interference.;

    Abstract : Although the yeast Candida glabrata is considered to be a part of the commensal microflora in healthy individuals, during the last years it has been frequently isolated from patients with mucosal and systemic fungal infections. Now it is considered as the second most frequently isolated pathogenic yeast after Candida albicans. Despite its name, C. READ MORE

  5. 3. Mapping the Rickettsia prowazekii genome

    Author : Alireza Zomorodipour; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Rickettsia prowazekii is a member of alpha proteobacteria and the etiologic agent of epidemictyphus. Besides its pathogenicity as an obligate intracellular parasite it has been considered as amodel organism in a variety of studies.We have established a collection of overlapping clones, covering nearly the complete R.prowazekii genome. READ MORE

  6. 4. Genome-plasticity and adaption in Helicobacter pylori

    Author : Christina Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Helicobacter pylori is a gastric bacterial pathogen that infects an estimated half. of the human population. The infection is primarily acquired during early childhood and causes a persistent infection that is usually not eradicated by the host immune system. Although most infected individuals. READ MORE

  7. 5. Investigation of Mechanics of Mutation and Selection by Comparative Sequencing

    Author : Michael C. Zody; Kerstin Lindblad-Toh; Leif Andersson; Chad Nusbaum; Henrik Kaessmann; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; chicken; chimpanzee; human; evolution; segmental duplication; structural variation; chromosomal rearrangement; comparative genomics; positive selection; selective sweep; Genetics; Genetik; Genetics; genetik;

    Abstract : The process of evolution is of both scientific and medical interest. This thesis presents several studies using complete genomic reference sequences, comparative genomic data, and intraspecific diversity data to study the two key processes of evolution: mutation and selection. READ MORE