Search for dissertations about: "Global Markers"

Showing result 1 - 5 of 78 swedish dissertations containing the words Global Markers.

  1. 1. Towards explaining the Swedish epidemic of celiac disease an epidemiological approach

    University dissertation from Umeå : Umeå Universitet

    Author : Anna Myléus; Umeå universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiac disease; epidemiology; etiology; infant feeding; infections; prevalence; screening; vaccinations; epidemiologi; Epidemiology;

    Abstract : Background: Celiac disease occurs worldwide in approximately 1% of the population, whereof the majority of cases are undiagnosed. Sweden experienced an epidemic (1984-1996) of clinically detected celiac disease in children below 2 years of age, partly attributed to changes in infant feeding. READ MORE

  2. 2. Mass screening for celiac disease in 12-year-olds Finding them and then what?

    University dissertation from Umeå : Umeå universitet

    Author : Anna Rosén; Umeå universitet.; Umeå universitet.; [2012]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescent; celiac disease; children; coeliac disease; focus groups; mass screening; qualitative methodology; questionnaire; transglutaminase antibodies; epidemiologi; Epidemiology; Public health; folkhälsa;

    Abstract : Background Mass screening for celiac disease (CD) as a public health intervention is controversial. Before implementation, a suitable screening strategy should be outlined, and the acceptability of the screening scrutinized. Also, the benefits of early detection and possible negative consequences should be explored and compared. READ MORE

  3. 3. Identifying risk of type 2 diabetes epidemiologic perspectives from biomarkers to lifestyle

    University dissertation from Umeå : Folkhälsa och klinisk medicin

    Author : Margareta Norberg; Umeå universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes mellitus; metabolic syndrome; prediction; stress; social support; smokeless tobacco; risk; obesity; lifestyle; psychosocial; clinical markers; case-referent study; cohort study; MEDICINE Social medicine Public health medicine research areas Epidemiology; MEDICIN Socialmedicin Folkhälsomedicinska forskningsområden Epidemiologi;

    Abstract : Type 2 diabetes is a significant health problem because of its high prevalence and strong association with cardiovascular morbidity and mortality. An increase of type 2 diabetes is predicted due to increasing obesity and sedentary lifestyle habits. READ MORE

  4. 4. Method Development in Quantitative and Structural Proteomics using Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Charlotte Hagman; Uppsala universitet.; [2005]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Cerebrospinal Fluid; Electrospray Ionization; Fourier Transform Ion Cyclotron Resonance Mass Spectrometry; Global Markers; High Performance Liquid Chromatography; Gas-Phase Exchange; Hydrogen Deuterium Exchange; Plasma; Protoemics; Quantification; Structural Elucidation; Bioteknik; TECHNOLOGY Bioengineering; TEKNIKVETENSKAP Bioteknik;

    Abstract : In this thesis, methods for studying different aspects of proteomics were developed with Fourier Transform Ion Cyclotron Resonance, (FTICR), mass spectrometry. The FTICR technique provides ultra-high mass resolving power, mass accuracy at sub ppm level and sensitivity in the attomole region. READ MORE

  5. 5. Genomic and transcriptomic sequencing in chronic lymphocytic leukemia

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Diego Cortese; Uppsala universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic; lymphocytic; leukemia; CLL; genomics; transcriptomics; DNA; RNA; mutations; NGS; whole-exome; sequencing; prognostic; markers; TP53; SF3B1; RPS15; relapse; stereotyped; subsets.;

    Abstract : Identification of recurrent mutations through next-generation sequencing (NGS) has given us a deeper understanding of the molecular mechanisms involved in chronic lymphocytic leukemia (CLL) development and progression and provided novel means for risk assessment in this clinically heterogeneous disease. In paper I, we screened a population-based cohort of CLL patients (n=364) for TP53, NOTCH1, SF3B1, BIRC3 and MYD88 mutations using Sanger sequencing, and confirmed the negative prognostic impact of TP53, SF3B1 or NOTCH1 aberrations, though at lower frequencies compared to previous studies. READ MORE