Search for dissertations about: "Glutathione S-transferase"
Showing result 1 - 5 of 38 swedish dissertations containing the words Glutathione S-transferase.
-
1. The significance of glutathione S-transferases in biochemical toxicology : kinetic and binding studies designed to establish a mechanism of action of glutathione S-transferase A from rat liver
Abstract : .... READ MORE
-
2. Diet, lifestyle, antioxidants, and biomarkers of cancer risk - an epidemiological report from the Malmö Diet and Cancer cohort
Abstract : This thesis examines associations between a number of epidemiological or biological markers of cancer risk and oxidative stress, in order to achieve a better understanding of how diet, lifestyle, and genetic factors contribute to the occurrence of oxidative stress. Data from the Malmö Diet and Cancer (MDC) cohort was used. READ MORE
-
3. Isolation and characterization of glutathione S-transferases from various animal sources
Abstract : In the present investigation several forms of glutathione S-transferase were found in preparations of rat liver, rat lung, adult human liver, fetal human liver and whole earthworms. Human placenta, however, appeared to contain only one form of glutathione S-transferase. READ MORE
-
4. Microsomal glutathione transferase : studies on the kinetic mechanism, species variety, binding properties and substrate measurement
Abstract : Microsomal glutathione transferase (MGST) is a membrane bound detoxification enzyme, which has been purified from different species including rat, mouse, human, frog, and fish. The rat MGST1 is localized predominantly in the liver microsomes and the outer mitochondrial membrane. READ MORE
-
5. Oxidative damage and the DNA glycosylase MutYH
Abstract : The DNA glycosylase MutYH is highly conserved throughout evolution, and homologs are found in most eukaryotes and prokaryotes examined. MutYH functions as a base excision repair DNA glycosylase that excises adenines misincorporated opposite 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), one of the most stable products of oxidative DNA damage. READ MORE