Search for dissertations about: "Graft Rejection : therapy"

Showing result 1 - 5 of 21 swedish dissertations containing the words Graft Rejection : therapy.

  2. 1. Experimental studies on xenograft rejection

    Author : Guosheng Wu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The use of animal organs and tissues may provide a solution to the severe and worsening shortage of human grafts. The aims of the present experimental studies were to provide a better understanding of the rejection mechanisms and give new clues for prevention of xenorejection, thereby hopefully contributing to the development of clinical xenotransplantation. READ MORE

  4. 2. Studies of Acute Rejection Using Contrast Agents and Magnetic Resonance Imaging

    Author : Eva Penno; Håkan Ahlström; Cecilia Johnsson; Lars Johansson; Peter Leander; Uppsala universitet; []
    Keywords : Radiology; Magnetic resonance imaging; contrast agents; organ transplantation; acute rejection; Radiologisk forskning;

    Abstract : Solid organ transplantation is today an established form of treatment for end-stage organ disease. Monitoring of graft function and pharmacological therapy constitutes a maze of clinical observations and histological evaluations of biopsy specimens; with the biopsy results playing a decisive role. READ MORE

  5. 3. Inhibition of acute allogaft rejection - experimental transplant studies with biological and chemical immunosuppressants

    Author : Zhongquan Qi; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; tacrolimus; MNA; leflunomide; cyclosporine; drug effects; graft survival; immunosuppression; heart; animal; transplantation; Immunologi; serologi; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : In clinical transplantation immunosuppressive agents are used in combination with the objective to achieve additive effects and less toxicity. A large number of novel drugs are candidates for clinical introduction at this time and experiments in animal models have an important role to play. READ MORE

  6. 4. Strategies to improve macroencapsulated islet graft survival

    Author : Anne Sörenby; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic immunosuppressive therapy may have severe side-effects. In cell transplantation, the graft can be encapsulated within a membrane chamber, providing a physical barrier against the immune system. The cell graft then becomes dependent on the diffusion of nutrients and oxygen from the surrounding microcirculation. READ MORE

  7. 5. Alloreactivity in stem cell transplantation

    Author : Anna Nordlander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Acute graft-versus-host disease (GVHD), relapse and graft rejection are the main complications after allogeneic hematopoietic stem cell transplantation (HSCT). The aim of this thesis was to achieve a better understanding of the alloreactivity seen after HSCT, focusing on graft rejection, but also including the graft-versus-leukemia (GVL) effect and GVHD. READ MORE