Search for dissertations about: "H-PHOSPHONOTHIOATE DIESTERS"
Found 2 swedish dissertations containing the words H-PHOSPHONOTHIOATE DIESTERS.
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1. Studies on Oxidative Couplings in H-Phosphonate Chemistry
Abstract : In this thesis oxidative coupling of H-phosphonate and H phosphonothioate diesters with different alcohols and amines are presented. Since the reactions with alcohols previously have been particularly unfavourable due to competing side reactions, a modified protocol leading to high coupling yields of structurally diverse hydroxylic components was developed. READ MORE
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2. Studies on the synthesis of nucleotide analogues containing P-F and P-Se bonds
Abstract : In the present work, new synthetic approaches to the synthesis of nucleoside phosphorofluoridate and phosphorofluoridothioate diesters have been developed. These procedures involve either oxidative transformation of the corresponding H-phosphonate or H-phosphonothioate diesters in the presence of fluoride anion or iodine-promoted desulfurization of phosphorothioate or phosphorodithioate diesters in the presence of fluoride anion. READ MORE