Search for dissertations about: "H2AFX"

Found 2 swedish dissertations containing the word H2AFX.

  1. 1. The Neuroblastoma Genome and Epigenome - Patient Stratification and Identification of Candidate Genes

    Author : Helena Carén; Göteborgs universitet; []
    Keywords : cancer; neuroblastoma; epigenetics; DNA methylation; microarray; tumor suppressor gene; tumor; embryonal; neural crest; bisulfite sequencing; 1p36; 11q; MYCN; CASZ1; PIK3CD; PRKCDBP; SCNN1A; TGFBI; DHRS3; KRT19; DUSP23; APITD1; H2AFX;

    Abstract : Neuroblastoma (NB) is a tumor of the sympathetic nervous system, and the most common extracranial tumor of childhood. The prognosis for high-stage NBs is still poor, with survival rates of about 35%. Side-effects of treatment in these young children can also be severe. READ MORE

  2. 2. Molecular characterization of neuroblastoma tumors - a basis for personalized medicine

    Author : Hanna Kryh; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; Cancer; Tumor; SNP-array; Micro array; DNA copy number;

    Abstract : Neuroblastoma is a very heterogeneous tumor, with a clinical course ranging from spontaneous regression to aggressive tumor growth. A proper stratification of the patients into different risk groups is therefore important in order to provide the most suitable treatment for each patient. READ MORE