Search for dissertations about: "HBV"

Showing result 1 - 5 of 61 swedish dissertations containing the word HBV.

  2. 1. Hepatitis B virus RNA in serum and liver tissue - quantification using digital PCR

    Author : Kasthuri Prakash; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; NTCP; HBV DNA; HBV RNA; subviral particles; integrations; droplet digital PCR;

    Abstract : Hepatitis B virus (HBV) infection is a global health issue that is responsible for approximately 900,000 deaths each year, by inducing liver cirrhosis and hepatocellular carcinoma (HCC). A few markers are used to classify HBV infection and monitor treatment efficacy, including HBV DNA, surface antigen (HBsAg) and e antigen (HBeAg) in serum as well as HBV DNA and RNA in liver tissue. READ MORE

  4. 2. Hepatitis B virus infection and genomic changes from a long-term perspective

    Author : Jonas Bläckberg; Sektion III; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; cor promoter; precore; occult infection; HBV; mutation;

    Abstract : Hepatitis B virus is a non-cytopathic virus with a small, circular, partially double-stranded DNA of 3.2 kb. It causes acute and chronic inflammatory liver disease and hepatocellular carcinoma (HCC). Retesting of stored sera from an outbreak of acute hepatitis in 1969-72 allowed identification of 126 cases of acute hepatitis B. READ MORE

  5. 3. Structure and Dynamics of the Hepatitis B Virus Encapsidation Signal Revealed by NMR Spectroscopy

    Author : Sara Flodell; Stephan Grzesiek; Umeå universitet; []
    Keywords : HBV; RNA; isotope labelling; NMR; structure determination; medicinsk biokemi; Medical Biochemistry;

    Abstract : This thesis describes the study of the three-dimensional structure and dynamics of the hepatitis B virus (HBV) encapsidation signal, epsilon, by means of nuclear magnetic resonance (NMR) and mutational data. HBV replicates by reverse transcription of an RNA pregenome into the viral DNA genome, which becomes enclosed in viral particles (encapsidation). READ MORE

  6. 4. Prevalance and prevention of sexually transmitted viral infections in the Bolivian Amazonas

    Author : Marianela Patzi Churqui; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sexually transmitted infections; indigenous women; Bolivian Amazonas; medical plants; microbicides; cytokines; HSV-2; HPV; HBV;

    Abstract : This thesis investigates the prevalence of sexually transmitted viral infections in women living in the Amazonas region of Bolivia and explores whether Bolivian medical plants can affect the immune system and prevent or treat infections with Herpes simplex virus type 2 (HSV-2) and inflammation. My PhD project was financed by the Swedish International Development Cooperation Agency (SIDA), and I did my work alternately in Bolivia and in Sweden. READ MORE

  7. 5. Building a coherent hydro-climatic modelling framework for the data limited Kilombero Valley of Tanzania

    Author : Alexander Koutsouris; Steve W. Lyon; Jan Seibert; Mekonnen Gebremichael; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hydrology; Precipitation; Recession analysis; End - member mixing analysis; EMMA; GLUE; HBV; down scaling; Quantile mapping; CFSR; CMORPH; CRU; GPCC; ERA - i; MERRA; TRMM; UDEL; Satellite; Reanalysis; Kilombero; Tanzania; Eastern Africa; Africa; Physical Geography; naturgeografi;

    Abstract : This thesis explores key aspects for synthesizing data across spatiotemporal scales relevant for water resources management in an Eastern Africa context. Specifically, the potential of large scale global precipitation datasets (GPDs) in data limited regions to overcome spatial and temporal data gaps is considered. READ MORE