Search for dissertations about: "HGF"

Showing result 1 - 5 of 34 swedish dissertations containing the word HGF.

  2. 1. Growth factor receptor signalling in thyrocytes of normal and neoplastic origin

    Author : Daniel Bergström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; thyroid; carcinoma; HGF; Met; TGF-β; EGF; receptor signalling; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Cellular growth and function are controlled by stimulatory and inhibitory factors actingthrough specific receptors. The present thesis focuses on the role of growth factors, theirreceptors and signalling pathways in normal and neoplastic thyroid epithelial cell biology. READ MORE

  4. 2. A microscopic investigation of miR-34c and miR-205 in Prostate Cancer

    Author : Zandra Hagman; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; prostate cancer; androgen receptor; MET; HGF; miR-34c; miR-205; AGO2-RIP-Chip; noncoding RNA;

    Abstract : The complex genetics of cancer allows tumors to grow and spread undeterred by the control mechanisms of the cell. The importance of protein-coding genes in tumorigenesis is well established. READ MORE

  5. 3. Hormonal regulation of liver and tumor growth

    Author : Ville Wallenius; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver; cytokine; interleukin-6; tumor necrosis factor; primary liver growth promoter; cyproterone acetate; nafenopin; hepatocyte growth factor; HGF receptor; tumor; sarcoma; N-terminal; truncated;

    Abstract : The aims of this thesis were to investigate the regulatory functions of interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a) on liver growth, and the importance of hepatocyte growth factor (HGF) and the HGF receptor (Met) for growth of mesenchyme-derived tumors. The studies on different types of liver growth, measured as weight, DNA and protein content, and DNA synthesis, were performed on mice lacking the IL-6 or the TNF receptor-1 gene back-crossed to the C57bl/6 strain. READ MORE

  6. 4. Hepatocyte growth factor : Studies on local and systemic release and effects during infectious disease; in vivo and in vitro

    Author : Fariba Nayeri; Minoca Niste'r; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The interaction of mesenchymal and epithelial cells that occurs after organ injuries results in enhanced production of cytokines, such as hepatocyte growth factor (HGF). HGF is a glycoprotein with unique properties that contribute to wound healing after injuries. READ MORE

  7. 5. The role of peridontitis and hepatocyte growth factor in systemic inflammation

    Author : Johanna Lönn; Torbjörn Bengtsson; Fariba Nayeri; Anders Gustafsson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatocyte growth factor; Porphyromonas gingivalis; periodontitis; systemic inflammation; coronary artery disease; chronic renal failure; lipoxin; Biomedicin; Biomedicine;

    Abstract : An essential goal in addressing inflammation is the return of tissue to homeostasis. Persistent infections often cause prolonged response and accumulation of immune cells, inducing imbalance in pro- and anti-inflammatory mediators, tissue destruction, and chronic inflammation. READ MORE