Search for dissertations about: "HMG-1"

Found 2 swedish dissertations containing the word HMG-1.

  2. 1. Cytokines and cytokine-directed intervention in experimental arthritis

    Author : Karin Palmblad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : pro-inflammatory cytokines; collagen-induced arthritis; CNI-1493; HMG-1;

    Abstract : Rheumatoid arthritis (RA) is a common chronic autoimmune and inflammatory disease. Although the etiology of RA remains unknown, a general understanding of the pathogenesis is steadily increasing. The macrophage products tumor necrosis factor (TNF) and interleukin 1 (IL-1) are recognized as pivotal mediators in the arthritic process. READ MORE

  4. 2. Regulation of HIV-1 provirus transcription

    Author : Mojgan H Naghavi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Key words- HIV-1; LTR; transcription; subtypes; phylogenetic analysis; NFkappaB; USF; MCEF; HMG-1 DSP1; Dorsal.;

    Abstract : Transcription of the HIV-genome is regulated by the interaction of viral long terminal repeat (LTR) cis-acting sequences with a complex of viral regulatory proteins and cellular transcription factors. The complex interplay between the cellular-, and/or viral proteins and LTR of different subtypes may play a role in the control of HIV-1 latency versus activation. READ MORE