Search for dissertations about: "HPC POLYMER PROFILE IN THESIS"

Found 1 swedish dissertation containing the words HPC POLYMER PROFILE IN THESIS.

2. 1. Characterization of the Mechanisms of Drug Release from Polymer-Coated Formulations using Experiments and Modelling

   Author : Mariagrazia Marucci; Avdelningen för kemiteknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ethyl cellulose; Release mechanism; coating; polymer blend; modelling; ESPI; diffusion; osmotic pumping; SEM; single pellet; CLSM; hydroxypropyl cellulose; multiple-unit release;

   Abstract : The main objectives of the work presented in this thesis were to develop new experimental methods to improve the understanding of the release mechanism from a coated formulation and to develop new mechanistic models to describe the release process for pellets coated with a semi-permeable film. Another aim was to characterize the release mechanism from a formulation coated with films made of a blend of a water-insoluble polymer, ethyl cellulose (EC), and a water-soluble polymer, hydroxypropyl cellulose (HPC). READ MORE