Search for dissertations about: "HPV16 - E6 gene - polymorphism"

Found 3 swedish dissertations containing the words HPV16 - E6 gene - polymorphism.

  2. 1. The role of human papillomavirus in adenocarcinoma of the uterine cervix

    Author : Sonia Andersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Cervix; Adenocarcinoma; HPV; Prevalence; Age; PCR; DNA-sequencing; p53; HPV16 - E6 gene - polymorphism;

    Abstract : Background: Cervical carcinoma is the third most common malignant disease in women worldwide. The absolute frequency of adenocarcinoma of cervix uteri has increased during the last decade and accounts for about 15-20% of invasive cervical cancers. READ MORE

  4. 2. Molecular biological techniques as a tool in diagnostic pathology : Applications in B-cell lymphoproliferative disease, medullary thyroid carcinoma and cervical carcinoma

    Author : Mansour Alemi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; PCR-SSCP; MTC; RET mutation; Lymphoma; HPV; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Identification of malignancy associated with mutations in gene sequences requires detection ofas little as a single base difference. A powerful technique in mutation detection is polymerasechain reaction (PCR) followed by single-strand conformational polymorphism (SSCP) andsequencing. READ MORE

  5. 3. Identifying Risk Genes for Cervical Cancer : Using Affected Sib-Pairs and Case-Control Materials from Sweden

    Author : Malin Engelmark; Ulf Gyllensten; Dan Holmberg; Uppsala universitet; []
    Keywords : Medicine; Cervical cancer; HPV; Affected sib-pairs; HLA; Fas; Genomewide scan; 9q32; TSCOT; Medicin;

    Abstract : Cervical cancer is a multifactorial disease. Infection by oncogenic types of the human papillomavirus (HPV) is the major environmental risk factor and host genetic susceptibility also influences disease development. The aim of this thesis is to identify and analyse risk genes involved in the genetic predisposition to cervical carcinoma. READ MORE