Search for dissertations about: "HSP40"
Found 3 swedish dissertations containing the word HSP40.
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1. The Molecular Chaperone DNAJB6 - A Suppressor of Disease Related Amyloid Fibril Formation
Abstract : Several neurodegenerative diseases are caused by peptides or proteins forming amyloid fibrils such as the Aβ peptide involved in Alzheimer’s disease and the huntingtin exon-1 with a prolonged polyglutamine (polyQ) stretch involved in Huntington’s disease. The ability to form amyloid fibrils is an intrinsic feature in all proteins. READ MORE
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2. Mammalian sperm flagella and cilia
Abstract : In mammals, both sperm flagella and cilia are axoneme-containing organelles. The sperm flagella are major parts of the spermatozoa that are male gametes produced in the testis from progenitor spermatogonia through a process called spermatogenesis. READ MORE
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3. Regulation of cellular Hsp70 : Proteostasis and aggregate management
Abstract : Proteins have to be folded to their native structures to be functionally expressed. Misfolded proteins are proteotoxic and negatively impact on cellular fitness. To maintain the proteome functional proteins are under the constant surveillance of dedicated molecular chaperones that perform protein quality control (PQC). READ MORE