Search for dissertations about: "Helena Jones"

Found 1 swedish dissertation containing the words Helena Jones.

2. 1. THE ROLE OF PHOSPHODIESTERASE 3B IN CAMP-MEDIATED REGULATION OF INSULIN SECRETION

   Author : Helena Jones; Signaltransduktionsforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cAMP; PDE3B; exocytosis; insulin; diabetes; Medicine human and vertebrates ; Medicin människa och djur ; diabetologi; sekretion; Endokrinologi; diabetology; Endocrinology; secreting systems;

   Abstract : Type 2 diabetes mellitus (T2DM) is characterized by various combinations of ?-cell failure and insulin resistance leading to hyperglycemia and glucose intolerance. In order to maintain glucose tolerance in the insulin resistance state, increased insulin secretion is a requirement and it is because of inadequate islet adaptation that glucose intolerance develops in T2DM. READ MORE