Search for dissertations about: "Hematopoietic Stem Cell Transplantation"
Showing result 1 - 5 of 146 swedish dissertations containing the words Hematopoietic Stem Cell Transplantation.
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1. Hematopoietic stem cell dynamics during regenerative stress
Abstract : .... READ MORE
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2. Identification of Unique Hematopoietic Stem Cell Properties
Abstract : Hematopoietic stem cells (HSC) are sufficient and required for life long production of all blood cell lineages. Steady state HSCs are largely quiescent and we demonstrate that the kinetics of HSC cell cycling are slower compared to more committed progenitor cells also during expansion and self-renewal ex vivo and in physiological conditions. READ MORE
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3. Hematopoietic stem and progenitor cells and potentials for application in fetal cell replacement therapy
Abstract : Fetal cell replacement therapy or in utero hematopoietic cell transplantation (IUHCT) is proposed as a non-myeloablative alternative to bone marrow transplantation (BMT) for a number of inborn immunologic, hematologic and metabolic disorders. IUHCT represents the method through which variable amounts of natural or genetically modified hematopoietic cells can be transferred to the fetal recipient in hope of correcting the disorder and preventing postnatal permanent organ damage. READ MORE
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4. Cellular and Molecular Pathways Governing Hematopoietic Stem Cell Fate
Abstract : Hematopoietic Stem Cells (HSCs) have been defined to have abilities of both self-renewal and multi-lineage differen-tiation. The balance between these abilities is rigorously controlled under steady-state status (homeostasis) and when the normal processes of self-renewal and differentiation become deregulated, a disorder of blood system (such as leukemias) can occur. READ MORE
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5. Cytokine Regulation of Hematopoietic Stem Cells and Lymphopoiesis
Abstract : Large numbers of blood cells need to be continuously replaced in order to sustain the crucial functions of the immune system, oxygen transport and blood clotting. The large diversity of cell types required to maintain the integrity of the blood system are all produced from blood forming or hematopoietic stem cells (HSCs). READ MORE